|1.||Chow, Kuan-Chih: 9 articles (02/2014 - 05/2002)|
|2.||Lin, Tze-Yi: 5 articles (02/2014 - 05/2002)|
|3.||Simpkins, Henry: 4 articles (06/2015 - 04/2002)|
|4.||Chiang, Yung-Yen: 3 articles (02/2014 - 07/2009)|
|5.||Chiou, Shiow-Her: 3 articles (09/2013 - 03/2003)|
|6.||Chen, Chih-Yi: 3 articles (09/2013 - 05/2002)|
|7.||Parekh, Hemant K: 3 articles (05/2008 - 04/2002)|
|8.||Wang, Liang-Shun: 3 articles (07/2006 - 08/2004)|
|9.||Chen, Jianli: 2 articles (06/2015 - 05/2008)|
|10.||Chiang, I-Ping: 2 articles (02/2014 - 03/2003)|
04/01/2007 - "Dihydrodiol dehydrogenase in drug resistance and sensitivity of human carcinomas."
04/26/2002 - "Increased expression of dihydrodiol dehydrogenase induces resistance to cisplatin in human ovarian carcinoma cells."
10/01/2004 - "We have recently demonstrated that overexpression of dihydrodiol dehydrogenase (DDH) in human ovarian carcinoma cells (2008/C13*) is associated with cisplatin and carboplatin resistance. "
10/01/2004 - "Ubiquitous induction of resistance to platinum drugs in human ovarian, cervical, germ-cell and lung carcinoma tumor cells overexpressing isoforms 1 and 2 of dihydrodiol dehydrogenase."
07/01/2001 - "In this study, rat liver 3alpha-hydroxysteroid/dihydrodiol dehydrogenase (AKR1C9) was stably transfected into human breast carcinoma (MCF-7) cells, which represent a null-environment for AKR expression, to detect the formation of PAH o-quinones in a cellular context and the cellular consequences of o-quinone formation. "
|2.||Lung Neoplasms (Lung Cancer)
06/01/2015 - "Dihydrodiol dehydrogenase appears to play a role in cisplatin resistance in cervical, ovarian and lung cancer cells which includes mitochondrial membrane depolarization, ROS production and activation of the JNK pathway. "
06/01/2015 - "Downregulation of dihydrodiol dehydrogenase in the cisplatin-resistant cervical and lung cancer cell lines resulted in increased drug sensitivity with detectable production of ROS and activation of the JNK/p38 pathways; however, downregulation of thioredoxin in the cervical cells had minimal effect. "
01/01/2007 - "A possible role for dihydrodiol dehydrogenase in the formation of benzo[a]pyrene-DNA adducts in lung cancer cells and tumor tissues."
01/01/2007 - "In the present study, we have evaluated the roles of CYP1A1 and dihydrodiol dehydrogenase (DDH) in the formation of benzo[a]pyrene (BaP) DNA adducts in various lung cancer cell lines. "
|4.||Ovarian Neoplasms (Ovarian Cancer)
04/01/2005 - "Overexpression of dihydrodiol dehydrogenase is associated with cisplatin-based chemotherapy resistance in ovarian cancer patients."
04/01/2005 - "Results of a recent study on human ovarian cancer cell lines indicated that overexpression of dihydrodiol dehydrogenase (DDH) was associated with resistance to cisplatin and disease progression. "
|5.||Dupuytren Contracture (Dupuytrens Contracture)
05/01/2013 - "We noted a statistically significantly higher prevalence of the variants of the dihydrodiol dehydrogenase gene (rs2270941 and rs11666105) in the group with a positive familial history of Dupuytren's disease, in comparison with the group with a negative familial history."
05/01/2013 - "The object of this study was the investigation of four common variants of single nucleotide polymorphisms of the aldehyde dehydrogenase H2 gene and dihydrodiol dehydrogenase gene and their association with the occurrence of Dupuytren's disease. "
|3.||Cytochrome P-450 CYP1A1 (CYP1A1)
|7.||3-hydroxysteroid dihydrodiol dehydrogenase
|9.||Messenger RNA (mRNA)
|1.||Drug Therapy (Chemotherapy)