|1.||Castanas, Elias: 4 articles (01/2013 - 04/2002)|
|2.||Tsapis, Andreas: 4 articles (01/2013 - 04/2002)|
|3.||Dillon, Stacey R: 4 articles (03/2011 - 01/2007)|
|4.||Gross, Jane A: 4 articles (03/2011 - 01/2004)|
|5.||Kampa, Marilena: 3 articles (01/2013 - 02/2012)|
|6.||Stathopoulos, Efstathios N: 3 articles (01/2013 - 02/2012)|
|7.||Notas, George: 3 articles (01/2013 - 02/2012)|
|8.||Pelekanou, Vassiliki: 3 articles (01/2013 - 02/2012)|
|9.||Abramowitz, Paul W: 3 articles (01/2011 - 01/2009)|
|10.||Morriss, Frank H: 3 articles (01/2011 - 01/2009)|
04/29/2015 - "A BCMA-targeted bispecific antibody presents a promising treatment option for multiple myeloma. "
09/01/2012 - "The present study found that BCMA concentrations were higher in the supernatants of cultured bone marrow mononuclear cells from multiple myeloma (MM) patients than in healthy subjects. "
04/15/2013 - "BCMA is a promising target for CAR-T cells in multiple myeloma."
04/15/2013 - "BCMA is a suitable target for CAR-expressing T cells, and adoptive transfer of anti-BCMA-CAR-expressing T cells is a promising new strategy for treating multiple myeloma."
04/15/2013 - "Importantly, anti-BCMA-CAR-transduced T cells recognized and killed primary multiple myeloma cells. "
|2.||Autoimmune Diseases (Autoimmune Disease)
06/01/2005 - "Neutralizing single-chain fragment variable (scFv) antibody against BLyS binding to its receptor BCMA has the potential to play a prominent role in autoimmune disease therapy. "
11/01/2003 - "Lupus erythematodes prone mice have elevated blood levels of BAFF, and treatment of these mice with the BAFF decoy receptor (BCMA-Ig) prevents the onset of this systemic autoimmune disease. "
04/27/2000 - "TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease."
08/01/2015 - "A BCMA-antibody-based therapy is therefore a promising option for the effective treatment of multiple myeloma and autoimmune diseases. "
01/01/2015 - "Together, shedding of BCMA by γ-secretase controls plasma cells in the bone marrow and yields a potential biomarker for B-cell involvement in human autoimmune diseases. "
07/01/2013 - "Immunohistochemically, lymphocytes infiltrating NB tumors from patients, with or without OMS, expressed BAFF, BAFF-R, and BCMA, whereas neuroblasts expressed BAFF and BCMA but not BAFF-R. "
07/01/2013 - "We investigated BAFF, BAFF-R, and BCMA expression in NB tumors associated or not with OMS. "
04/15/2013 - "The anti-BCMA-CAR-transduced T cells exhibited BCMA-specific functions including cytokine production, proliferation, cytotoxicity, and in vivo tumor eradication. "
01/01/2013 - "We show that in IHC, BAFF and APRIL as well as their cognate receptors (BCMA, TACI) and Fn14 expression correlate with tumor grade. "
11/15/2012 - "Our data, therefore, identify a novel APRIL/BCMA signaling pathway in HCC and suggest that APRIL could have a pleiotropic role in tumor biology."
|4.||T-Cell Lymphoma (Lymphoma, T Cell)
04/11/1994 - "In a previous study of a t(4;16)(q26;p13) translocation, found in a human malignant T-cell lymphoma the BCMA gene, located on chromosome band 16p13.1, has been characterized. "
11/01/1998 - "The BCMA gene is a new gene discovered by the molecular analysis of a t(4;16) translocation, characteristic of a human T cell lymphoma. "
|5.||Breast Neoplasms (Breast Cancer)
05/01/1998 - "In particular, an increased duration of BCMA before the first childbirth and over life was found to increase the risk of breast cancer (P < 0.001). "
05/01/2015 - "Studies of 4T1 orthotopic breast tumors in APRIL transgenic mice showed that an APRIL-enriched environment increased tumor growth and promoted lung metastasis associated with enhanced tumor cell proliferation; BCMA and TACI expression suggests that both participate in these processes. "
05/01/2015 - "Here, we show that several breast cancer cell lines express APRIL and both its receptors, B cell maturation antigen (BCMA) and transmembrane activator and CAML-interactor (TACI), independently of luminal or basal tumor cell phenotype, and that the mitogen-activated protein kinases p38, ERK1/2, and JNK1/2 are activated in response to APRIL. "
|1.||B-Cell Maturation Antigen
|5.||B-Cell Activating Factor
|6.||B-Cell Activation Factor Receptor
|7.||Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)
|8.||Messenger RNA (mRNA)
|9.||Proteins (Proteins, Gene)
|2.||Neonatal Intensive Care
|3.||Heterologous Transplantation (Xenotransplantation)