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cyanopindolol

Networked: 31 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Hrupka, Brian J: 1 article (01/2003)
2. Langhans, Wolfgang: 1 article (01/2003)
3. von Meyenburg, Claudia: 1 article (01/2003)
4. Bossone, C: 1 article (11/2001)
5. Piñeiro-Carrero, V: 1 article (11/2001)
6. Shea-Donohue, T: 1 article (11/2001)
7. Zhao, A: 1 article (11/2001)
8. Aubert, N: 1 article (01/2000)
9. Bloomquist, W: 1 article (01/2000)
10. Burlet, C: 1 article (01/2000)

Related Diseases

1. Body Weight (Weight, Body)
12/01/1997 - "2. Heart rate was dose-dependently increased by CGP 12177 and cyanopindolol by maximally 150 and 100 beats min(-1), yielding pED50 values of 8.0 and 7.3, respectively (pED50, -log10 of the dose in mol kg(-1) body weight i.v. causing the half-maximum effect), but not affected by the selective beta3-adrenoceptor agonist CL 316243 (pED50 > 6.0). "
02/01/1998 - "3. TG(mREN2)27-rats were characterized by arterial hypertension (TG 194+/-3.2 mmHg vs SD 136+/-2.9 mmHg systolic blood pressure), increased left ventricular weights (TG 4.3+/-0.3 vs SD 3.0+/-0.1 mg g(-1) body weight), decreased myocardial neuropeptide Y (NPY) concentrations (TG 1143+/-108 vs SD 1953+/-134 pg g(-1) wet weight), reduced beta-adrenoceptor densities (TG 51.1+/-1.9 vs SD 63.4+/-3.7 fmol mg[-1]) as assessed by [125I]-cyanopindolol binding studies, and increased Gi(alpha)-activities (TG 4151+/-181 vs SD 3169+/-130 densitometric units) as assessed by pertussis toxin catalyzed [32P]-ADP-ribosylation. "
02/01/1992 - "1. The long-term effects of sinoaortic denervation on the development of left ventricular hypertrophy (assessed by the measurement of the ratio (R): heart weight/total body weight and LVT: left ventricular thickness), myocardial beta-adrenergic receptivity (measured by [125I]-cyanopindolol binding and adenylate cyclase activity) and plasma catecholamine levels (measured by h.p.l.c.) were investigated in three groups of dogs: normotensive controls (group 1), dogs made hypertensive by sinoaortic denervation and evaluated 1 (group 2) and 18 months (group 3) later. "
2. Hypertension (High Blood Pressure)
3. Parkinson Disease (Parkinson's Disease)
4. Neoplasms (Cancer)
5. Lymphoma (Lymphomas)

Related Drugs and Biologics

1. Adrenergic Receptors (Adrenergic Receptor)
2. Pertussis Toxin
3. Neuropeptide Y
4. Adenylyl Cyclases (Adenylyl Cyclase)
5. Adrenergic Agents (Adrenergic Drugs)
6. beta Adrenergic Receptors
7. Serotonin Receptors
8. Prazosin (Minipress)
9. Ligands
10. Ketanserin

Related Therapies and Procedures

1. Denervation