|1.||Matsui-Yuasa, Isao: 5 articles (04/2014 - 02/2002)|
|2.||Murakami, Akira: 5 articles (01/2009 - 02/2002)|
|3.||Azuma, Hideki: 4 articles (02/2015 - 03/2006)|
|4.||Kojima-Yuasa, Akiko: 4 articles (04/2014 - 03/2006)|
|5.||Ohigashi, Hajime: 4 articles (01/2009 - 02/2002)|
|6.||Kizaki, Masahiro: 3 articles (05/2015 - 05/2005)|
|7.||Kennedy, David Opare: 3 articles (05/2010 - 02/2002)|
|8.||Misawa, Takashi: 2 articles (05/2015 - 10/2008)|
|9.||Sagawa, Morihiko: 2 articles (05/2015 - 10/2008)|
|10.||Aoyama, Hiroshi: 2 articles (05/2015 - 10/2008)|
|1.||Ehrlich Tumor Carcinoma
02/20/2002 - "To further evaluate the efficacy of the anticancer activity of 1'-acetoxychavicol acetate (ACA), this study investigates the underlying mechanisms by which ACA induces death of Ehrlich ascites tumor cells. "
12/01/2000 - "The efficacy of the antitumor activity of 1'-acetoxychavicol acetate (ACA), reported to be a suppressor of chemically induced carcinogenesis, was evaluated in Ehrlich ascites tumor cells. "
12/01/2000 - "Apoptosis induced by 1'-acetoxychavicol acetate in Ehrlich ascites tumor cells is associated with modulation of polyamine metabolism and caspase-3 activation."
05/14/2010 - "Comparison of glutathione reductase activity and the intracellular glutathione reducing effects of 13 derivatives of 1'-acetoxychavicol acetate in Ehrlich ascites tumor cells."
01/01/2009 - "The effect of 1'-acetoxychavicol acetate (ACA), an anticarcinogenic compound naturally obtained from rhizomes and seeds of South East Asia plants, on the intracellular concentration of glutathione and the activities of enzymes related to glutathione metabolism was studied in Ehrlich ascites tumor cells. "
|2.||Aberrant Crypt Foci
05/01/1997 - "The modifying effect of dietary administration of a xanthine oxidase inhibitor 1'-acetoxychavicol acetate (ACA) present in an edible plant Languas galanga in Thailand on the development of azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF) was investigated in rats. "
05/01/1997 - "A xanthine oxidase inhibitor 1'-acetoxychavicol acetate inhibits azoxymethane-induced colonic aberrant crypt foci in rats."
09/01/1997 - "In our studies to find natural compounds with chemopreventive efficacy in foods, using azoxymethane (AOM)-induced colonic aberrant crypt foci and colonic mucosal cell proliferation as biomarkers, a xanthine oxidase inhibitor, 1'-acetoxychavicol acetate (ACA), present in the edible plant Languas galanga from Thailand was found to be effective. "
|3.||Asthma (Bronchial Asthma)
01/01/2012 - "The purpose of the current study was to determine whether a tropical ginger derived compound 1'-acetoxychavicol acetate (ACA), suppresses skin tumor promotion in K5.Stat3C mice. "
05/01/2015 - "1'-Acetoxychavicol acetate (ACA), which was isolated from the rhizomes of Zingiberaceae, exhibits various biological actions, including anti-inflammatory, anti-human immunodeficiency virus (HIV), and anti-cancer activities. "
06/01/2011 - "We describe that 1'-acetoxychavicol acetate (ACA), a component of Siamese ginger (Languas galanga), can suppress prostate tumor growth by largely abrogating angiogenesis. "
09/01/2007 - "1'-Acetoxychavicol acetate (ACA) has been shown to inhibit tumor cell growth, but there is limited information on its effects on cell signaling and the cell cycle control pathway. "
06/01/2005 - "1'-Acetoxychavicol acetate (ACA), extracted from rhizomes of the commonly used ethno-medicinal plant Languas galanga, has been found to suppress chemical- and virus-induced tumor initiation and promotion through a poorly understood mechanism. "
|5.||Breast Neoplasms (Breast Cancer)
11/01/2014 - "The purpose of this study is to investigate whether the natural agent 1'-acetoxychavicol acetate (ACA), derived from the rhizomes and seeds of Languas galanga, could suppress breast cancer metastasis by targeting STAT3 signaling pathway. "
09/28/2007 - "The tropical ginger compound, 1'-acetoxychavicol acetate (ACA) possesses cancer chemopreventive properties in several models but its effects on breast cancer have not been fully evaluated. "
11/01/2014 - "Small molecule 1'-acetoxychavicol acetate suppresses breast tumor metastasis by regulating the SHP-1/STAT3/MMPs signaling pathway."
|3.||Biological Markers (Surrogate Marker)
|9.||Glutathione (Reduced Glutathione)
|1.||Heterologous Transplantation (Xenotransplantation)