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kaur-16-en-15-ol

structure given in first source

Also Known As:

ent-kaur-16-en-15 beta-ol; kaurenol

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Diterpenes: 1470
      - kaur-16-en-15-ol: 2

Experts

1.	Chen, Xiaoming: 1 article (11/2010)
2.	Coates, Robert M: 1 article (11/2010)
3.	Morrone, Dana: 1 article (11/2010)
4.	Peters, Reuben J: 1 article (11/2010)

Related Diseases

1.	Dehydration (Water Stress) 11/01/2010 - "This recombinant AtKO (rAtKO) was used to carry out 18O2 labelling studies with ent-kaurene, and the intermediates ent-kaurenol and ent-kaurenal, to investigate the multifunctional reaction sequence; revealing catalysis of three hydroxylation reactions, which further requires dehydration at some stage. " 11/01/2010 - "Accordingly, following initial hydroxylation, ent-kaurenol must then be further hydroxylated to a gem-diol intermediate, and our data indicate that the subsequent reactions proceed via dehydration of the gem-diol to ent-kaurenal, followed by an additional hydroxylation to directly form ent-kaurenoic acid. "
2.	Edema (Dropsy) 09/21/2023 - "Kaurenol showed 53%, 64%, 64%, and 58% of inhibition in the acetic acid-induced writhing, second phase of formalin test, carrageenan and dextran-induced paw edema, respectively. " 09/21/2023 - "To this end, the following experiments were conducted to evaluated toxicity: locomotor performance and acute toxicity; nociception: acetic acid-induced writhing and formalin-induced antinociception; and anti-inflammatory activity: carrageenan and dextran-induced paw edema at 10, 20, and 40 mg/kg, and measurement of nitric oxide (NO), tumor necrosis factor alpha (TNF-α), interleukin-6 (IL-6), and interleukin-10 (IL-10) in macrophages at 1, 3, and 9 μg/ml. Kaurenol did not show significant locomotor changes, acute toxicity, and central analgesic activity in the first phase of formalin test at dosages tested. "

Related Drugs and Biologics

1.	Kaurane Diterpenes
2.	Acetic Acid (Vinegar)
3.	Interleukin-10 (Interleukin 10)
4.	Interleukin-6 (Interleukin 6)
5.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
6.	Nitric Oxide (Nitrogen Monoxide)
7.	Formaldehyde (Formol)
8.	Dihydrotachysterol (AT 10)
9.	Dextrans (Dextran)
10.	Carrageenan