gastric mucus glycoproteins

from glandular region of gastric mucosa; high molecular wt. glycoproteins consisting of large numbers of carbohydrate side chains attached to protein core through O-glycosidic linkages; possibly protects stomach from ulceration

Also Known As:

Networked: 54 relevant articles (0 outcomes, 8 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Albulescu, Alexandra: 1 article (01/2022)
2.	Costain, Gregory: 1 article (01/2022)
3.	Dell, Sharon D: 1 article (01/2022)
4.	Goczi, Adrienn N: 1 article (01/2022)
5.	Hall, David A: 1 article (01/2022)
6.	Hill, David B: 1 article (01/2022)
7.	Kesimer, Mehmet: 1 article (01/2022)
8.	Khan, Meraj: 1 article (01/2022)
9.	Knowles, Michael: 1 article (01/2022)
10.	Liu, Zhen: 1 article (01/2022)

Related Diseases

1.	Gallstones (Gallstone) 12/01/1995 - "Possible role of hepatic bile mucus glycoprotein in development of intrahepatic gallstones." 01/01/1987 - "These results are consistent with biliary mucus glycoprotein being involved in the initial stages of gallstone formation but not in subsequent growth." 04/01/1986 - "Quantitative and qualitative comparison of gall bladder mucus glycoprotein from patients with and without gall stones." 03/01/1986 - "There was a striking increase in the amount of mucus glycoprotein in the gallbladder bile of the sludge group compared with the gallstone and control group. " 12/01/1995 - "To study the role played by hepatic bile mucus glycoprotein in the development of hepatolithiasis, mucus glycoprotein, isolated from the bile of patients with intrahepatic gallstones by gel filtration and ultracentrifugation, was examined for precipitability in control hepatic bile obtained postoperatively from patients successfully treated for cholecysto- and/or choledocho-lithiasis. "
2.	Ulcerative Colitis 07/01/1993 - "Studies have been made of mucus glycoprotein biosynthesis in different regions of the lower gastrointestinal tract in normal patients and those with ulcerative colitis (UC), active or inactive, by means of 3H-glucosamine (3H-GlcNH2)--35S-sulphate double labelling of epithelial biopsy specimens under culture conditions. " 02/01/1988 - "In vitro mucus glycoprotein production by colonic tissue from patients with ulcerative colitis." 01/01/1995 - "This study shows that mucus glycoprotein synthesis is reduced in inactive ulcerative colitis, rising to normal levels in active disease and that synthesis is increased in Crohn's disease. "
3.	Pancreatic Neoplasms (Pancreatic Cancer) 06/15/1990 - "Purification and characterization of a peanut-agglutinin-binding pancreatic-cancer-related serum mucus glycoprotein." 06/01/1989 - "Previous studies have shown that sera from patients with pancreatic cancer often contain a mucus glycoprotein that expresses the oncofetal antigen galactose 1-3, N-acetyl galactosamine, which is the T blood group antigen and the binding site for the lectin peanut agglutinin (PNA). "
4.	Lithiasis 12/01/1995 - "To study the role played by hepatic bile mucus glycoprotein in the development of hepatolithiasis, mucus glycoprotein, isolated from the bile of patients with intrahepatic gallstones by gel filtration and ultracentrifugation, was examined for precipitability in control hepatic bile obtained postoperatively from patients successfully treated for cholecysto- and/or choledocho-lithiasis. "
5.	Critical Illness (Critically Ill) 01/01/1986 - "Several studies show that cimetidine protects the stomach from aspirin-induced mucosal damage; increases gastric mucus production and mucus glycoprotein content, which contributes to the protective action of mucus; increases mucosal secretion of bicarbonate; increases gastric mucosal blood flow, which prevents mucosal hypoxia seen in patients in shock or otherwise critically ill patients; increases endogenous mucosal prostaglandin synthesis; and increases the rate of epithelial cell renewal, a factor important to mucosal healing. "

Related Drugs and Biologics

1.	Glycoproteins (Glycoprotein)
2.	Antigens
3.	Peanut Agglutinin
4.	Cimetidine (Biomet)
5.	Bicarbonates (Hydrogen Carbonate)
6.	Aspirin (Acetylsalicylic Acid)
7.	Lectins
8.	Prostaglandins
9.	Galactose (Galactopyranose)
10.	Galactosamine

Related Therapies and Procedures

1.	Cholecystectomy
2.	Aftercare (After-Treatment)