flestolol

11/01/1987 - "Flestolol prevented initiation of tachycardia by causing block in anterograde AV nodal conduction. "
01/01/1986 - "Flestolol effectively reduced heart rate in patients with supraventricular tachyarrhythmia. "
11/01/1986 - "Safety and efficacy of flestolol, a new ultrashort-acting beta-adrenergic blocking agent, for supraventricular tachyarrhythmias."
01/01/1987 - "The average maximum reduction in isoproterenol tachycardia was in the range of 63% to 79% during flestolol infusion. "
05/01/1986 - "A dose-dependent attenuation of isoproterenol-induced tachycardia and increase in systolic blood pressure occurred with flestolol at doses ranging from 0.5 to 15.0 micrograms/kg/min. The average percent reduction in isoproterenol-induced tachycardia (beta-blockade) at each dose of flestolol, 0.5, 2.5, 5.0, 15.0, and 50.0 micrograms/kg/min, was 15.1%, 45.9%, 67.0%, 85.9%, and 90.3%, respectively. "

03/01/1988 - "Thus flestolol, with its unique pharmacokinetic profile and titrability, may be beneficial in the treatment of critically ill patients."
02/01/1990 - "Flestolol has an extremely short half-life, demonstrated by an 83% loss of effect within 25 min. Thus, flestolol allows easy titration of the effect, which might be a valuable property for its use in the treatment of critically ill patients. "

11/01/1986 - "Flestolol, a new ultrashort-acting (half-life 6.9 minutes) beta-blocking drug, was administered by intravenous infusion to 18 patients with new-onset atrial fibrillation or flutter and rapid ventricular response (120 beats/min or more for at least 30 minutes). "
07/01/1988 - "The ultrashort-acting beta blocker flestolol was studied during atrial pacing and atrial fibrillation (AF) in 10 patients with Wolff-Parkinson-White syndrome. "
07/01/1988 - "Effect of flestolol on ventricular rate during atrial fibrillation in Wolff-Parkinson-White syndrome."
11/01/1986 - "Flestolol is effective in slowing ventricular response in new-onset atrial fibrillation and flutter, maintains a therapeutic effect during continuous infusion and rapidly loses therapeutic effect when discontinued."

01/01/1986 - "In patients with unstable angina, flestolol infusion was found to be safe and effective in controlling chest pain. "

01/01/1986 - "In patients with unstable angina, flestolol infusion was found to be safe and effective in controlling chest pain. "