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delapril

RN refers to HCl; structure given in first source
Also Known As:
CV 3317; CV-3317; N-(2,3-dihydro-1H-inden-2-yl)-N-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)alanyl)glycine; derapril
Networked: 87 relevant articles (20 outcomes, 29 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Fogari, Roberto: 9 articles (01/2011 - 07/2003)
2. Mugellini, Amedeo: 7 articles (01/2011 - 07/2003)
3. Cremonesi, Giovanni: 6 articles (01/2012 - 05/2003)
4. Zoppi, Annalisa: 5 articles (01/2008 - 07/2003)
5. Preti, Paola: 3 articles (01/2008 - 07/2003)
6. Rinaldi, Andrea: 3 articles (01/2008 - 07/2003)
7. Zalvidea, S: 2 articles (01/2015 - 02/2012)
8. Thireau, J: 2 articles (01/2015 - 02/2012)
9. Richard, S: 2 articles (01/2015 - 02/2012)
10. Aimond, F: 2 articles (01/2015 - 02/2012)

Related Diseases

1. Hypertension (High Blood Pressure)
2. Heart Failure
3. Stroke (Strokes)
4. Myocardial Infarction
06/01/1995 - "TCV-116 and delapril each significantly attenuated the increases in left ventricular end diastolic pressure, left ventricular weight, right ventricular weight, and LVEDVI following myocardial infarction in both in WKY and SHR, and shifted pressure-volume curve significantly to the left. "
03/01/2013 - "Moreover, the benefits of delapril are not limited to hypertensive patients, but also in those with microalbuminuria, left ventricular hypertrophy, myocardial infarction or heart failure; delapril appears to be effective and well tolerated."
07/01/2003 - "Beneficial effects of angiotensin-converting enzyme inhibitor and nitrate association on left ventricular remodeling in patients with large acute myocardial infarction: the Delapril Remodeling after Acute Myocardial Infarction (DRAMI) trial."
09/01/1999 - "Because ACE inhibition is a recommended treatment for heart failure, this study was designed to test the effects on neurohumoral activation, hemodynamics, and left ventricular (LV) volume of the combination of an ACE inhibitor (delapril) with a DA2-dopaminergic receptor/alpha2-adrenoceptor agonist (CHF-1024) or a beta1-adrenoceptor antagonist (metoprolol) after a moderate to large myocardial infarction (MI) in rats. "
06/01/1995 - "The aims were (1) to investigate the effect of hypertention on left ventricular dilatation and haemodynamic alterations following acute myocardial infarction in spontaneously hypertensive rats (SHR) and normotensive rats (WKY); (2) to compare haemodynamic indices between the two groups; (3) to assess whether the angiotensin II type 1 receptor antagonist (AIIA), TCV-116, prevented left ventricular dilatation after myocardial infarction; and (4) to compare the effect of AIIA with that of the angiotensin converting enzyme (ACE) inhibitor, delapril. "
5. Albuminuria

Related Drugs and Biologics

1. manidipine
2. Hydrochlorothiazide (Esidrix)
3. Indapamide
4. Enalapril
5. Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)
6. Captopril (Capoten)
7. Losartan (Cozaar)
8. irbesartan
9. candesartan cilexetil (Amias)
10. Ramipril (Altace)

Related Therapies and Procedures

1. Aftercare (After-Treatment)
2. Oral Administration
3. Surgical Instruments (Clip)