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N- acetylmuramyl- alanyl- isoglutamine- alanyl- cholesterol

Also Known As:

3-O-(MDP-Ala)cholesterol; MDP-alanyl-cholesterol; MTP-CHOL; MTP-alanyl-3-O-cholesterol

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Amino Sugars: 110
  - Muramic Acids: 28
    - Acetylmuramyl-Alanyl-Isoglutamine: 467
      - N-acetylmuramyl-alanyl-isoglutamine-alanyl-cholesterol: 4
- Sugar Acids: 4
  - Muramic Acids: 28
    - Acetylmuramyl-Alanyl-Isoglutamine: 467
      - N-acetylmuramyl-alanyl-isoglutamine-alanyl-cholesterol: 4
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Glycopeptides: 1928
    - Acetylmuramyl-Alanyl-Isoglutamine: 467
      - N-acetylmuramyl-alanyl-isoglutamine-alanyl-cholesterol: 4
Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Cholestanes
      - Sterols: 2245
        Cholesterol: 67133
        Cholesterol Esters: 1623
        N-acetylmuramyl-alanyl-isoglutamine-alanyl-cholesterol: 4
      - Cholestenes
        Cholesterol: 67133
        Cholesterol Esters: 1623
        N-acetylmuramyl-alanyl-isoglutamine-alanyl-cholesterol: 4
Lipids: 114793
- Membrane Lipids: 1591
  - Sterols: 2245
    - Cholesterol: 67133
      - Cholesterol Esters: 1623
        N-acetylmuramyl-alanyl-isoglutamine-alanyl-cholesterol: 4

Related Diseases

1.	Neoplasms (Cancer) 12/30/1994 - "Treatment with muramyldipeptide (MDP) or a lipophilic derivative (MTP-Chol) included in nanocapsules renders macrophages cytostatic towards tumor cells. " 10/01/1985 - "The ability of liposomes containing a new lipophilic muramyl peptide derivative, MDP-L-alanyl-cholesterol (MTP-CHOL), to induce peritoneal macrophage cytostatic activity and alveolar macrophage cytotoxic activity toward tumor cell targets in vitro was determined. "
2.	Neoplasm Metastasis (Metastasis) 01/01/1991 - "The dose of MTP-Chol in each injection, and the tumour burden in the mice did not change the percentage inhibition of metastases significantly. " 05/01/1994 - "A lipophilic immunomodulator (MTP-Chol) was included in nanocapsules prepared from different polymers and the anti-metastatic effects of the resulting drug delivery systems were evaluated in a murine model of liver metastases. " 01/01/1991 - "A lipophilic muramylpeptide (MTP-Chol), capable of rendering macrophages cytostatic towards tumour cells, was encapsulated within polyisobutylcyanoacrylate nanocapsules and administered to mice carrying an experimental model of liver metastasis. "

Related Drugs and Biologics

1.	Cytostatic Agents
2.	Nanocapsules
3.	Polymers
4.	Peptides (Polypeptides)
5.	Liposomes (Liposome)
6.	Immunologic Factors (Immunomodulators)
7.	Enbucrilate
8.	Cholesterol