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2,6-dichloro-1,4-phenylenediamine
structure given in first source
Also Known As:
2,6-dichloro-p-phenylenediamine
Networked:
3
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amines: 4871
Polyamines: 3918
Diamines: 518
Phenylenediamines: 6
2,6-dichloro-1,4-phenylenediamine: 3
Aniline Compounds: 46
Phenylenediamines: 6
2,6-dichloro-1,4-phenylenediamine: 3
Related Diseases
1.
Carcinogenesis
03/01/1982 - "
Carcinogenesis Bioassay of 2,6-Dichloro-p-Phenylenediamine (CAS No. 609-20-1) in F344 Rats and B6C3F1 Mice (Feed Study).
"
01/01/1989 - "
Pancreatic tissue (original and recut sections) from Fischer 344 rats fed 2,6-dichloro-p-phenylenediamine in a chronic (2-year) carcinogenesis bioassay was evaluated for presence of pancreatic hepatocytes (PH) by light microscopy.
"
03/01/1982 - "
A carcinogenesis bioassay of 2,6-dichloro-p-phenylenediamine, a chemical intermediate, was conducted in groups of 50 F344 rats and B6C3F1 mice of either sex.
"
2.
Liver Cell Adenoma (Hepatocellular Adenoma)
01/01/1985 - "
2,6-Dichloro-p-phenylenediamine (DPA) was recently reported to induce hepatocellular adenomas and carcinomas in male and female B6C3F1 mice but not in F344 rats.
"
03/01/1982 - "
Under the conditions of this bioassay, 2,6-dichloro-p-phenylenediamine was carcinogenic for male and female B6C3F1 mice, causing increased incidences of combined hepatocellular adenomas and carcinomas, and for male B6C3F1 mice, causing an increased incidence of hepatocellular adenomas alone.
"
3.
Carcinoma (Carcinomatosis)
01/01/1985 - "
2,6-Dichloro-p-phenylenediamine (DPA) was recently reported to induce hepatocellular adenomas and carcinomas in male and female B6C3F1 mice but not in F344 rats.
"
03/01/1982 - "
Under the conditions of this bioassay, 2,6-dichloro-p-phenylenediamine was carcinogenic for male and female B6C3F1 mice, causing increased incidences of combined hepatocellular adenomas and carcinomas, and for male B6C3F1 mice, causing an increased incidence of hepatocellular adenomas alone.
"