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dimethyl hydrogen phosphite (dimethyl phosphite)
intermediate in production of insecticides or herbicides
Also Known As:
dimethyl phosphite
; dimethyl phosphonate; dimethylphosphite
Networked:
2
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Inorganic Chemicals: 9
Electrolytes: 16106
Ions: 7857
Anions: 3501
Phosphites: 28
dimethyl hydrogen phosphite: 2
Phosphorus Compounds: 84
Phosphorus Acids: 1
Phosphorous Acids: 20
Phosphites: 28
dimethyl hydrogen phosphite: 2
Organic Chemicals: 133
Organophosphorus Compounds: 300
Organophosphonates: 424
dimethyl hydrogen phosphite: 2
Related Diseases
1.
Carcinogenesis
11/01/1985 - "
NTP Toxicology and Carcinogenesis Studies of Dimethyl Hydrogen Phosphite (CAS No. 868-85-9) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
"
2.
Neoplasms (Cancer)
11/01/1985 - "
Dimethyl hydrogen phosphite did not induce any neoplasms in male or female mice.
"
11/01/1985 - "
There was equivocal evidence of carcinogenicity in female F344/N rats receiving dimethyl hydrogen phosphite, as shown by marginally increased incidences of alveolar/bronchiolar carcinomas of the lung and of neoplasms of the stomach.
"
11/01/1985 - "
Under the conditions of these gavage studies, there was clear evidence of carcinogenicity in male rats receiving dimethyl hydrogen phosphite, as shown by increased incidences of alveolar/bronchiolar adenomas, alveolar/bronchiolar carcinomas, and squamous cell carcinomas of the lung and of neoplasms of the forestomach.
"
3.
Squamous Cell Carcinoma (Epidermoid Carcinoma)
11/01/1985 - "
Under the conditions of these gavage studies, there was clear evidence of carcinogenicity in male rats receiving dimethyl hydrogen phosphite, as shown by increased incidences of alveolar/bronchiolar adenomas, alveolar/bronchiolar carcinomas, and squamous cell carcinomas of the lung and of neoplasms of the forestomach.
"
4.
Bronchiolo-Alveolar Adenocarcinoma (Adenocarcinoma, Bronchiolo Alveolar)
11/01/1985 - "
There was equivocal evidence of carcinogenicity in female F344/N rats receiving dimethyl hydrogen phosphite, as shown by marginally increased incidences of alveolar/bronchiolar carcinomas of the lung and of neoplasms of the stomach.
"
11/01/1985 - "
Under the conditions of these gavage studies, there was clear evidence of carcinogenicity in male rats receiving dimethyl hydrogen phosphite, as shown by increased incidences of alveolar/bronchiolar adenomas, alveolar/bronchiolar carcinomas, and squamous cell carcinomas of the lung and of neoplasms of the forestomach.
"
5.
Adenoma (Adenomas)
11/01/1985 - "
Under the conditions of these gavage studies, there was clear evidence of carcinogenicity in male rats receiving dimethyl hydrogen phosphite, as shown by increased incidences of alveolar/bronchiolar adenomas, alveolar/bronchiolar carcinomas, and squamous cell carcinomas of the lung and of neoplasms of the forestomach.
"