|1.||Gatouillat, Grégory: 1 article (12/2015)|
|2.||El btaouri, Hassan: 1 article (12/2015)|
|3.||Magid, Abdulmagid Alabdul: 1 article (12/2015)|
|4.||Bertin, Eric: 1 article (12/2015)|
|5.||Morjani, Hamid: 1 article (12/2015)|
|6.||Madoulet, Claudie: 1 article (12/2015)|
|7.||Lavaud, Catherine: 1 article (12/2015)|
|8.||Trivedi, R: 1 article (01/2014)|
|9.||Mishra, D P: 1 article (01/2014)|
|10.||Maurya, R: 1 article (01/2014)|
|1.||Myeloid Leukemia (Leukemia, Myelocytic)
01/01/2014 - "In this study, we report for the first time that Medicarpin (Med), a naturally occurring phytoalexin sensitizes myeloid leukemia cells to TRAIL-induced apoptosis. "
01/01/2014 - "Medicarpin, a legume phytoalexin sensitizes myeloid leukemia cells to TRAIL-induced apoptosis through the induction of DR5 and activation of the ROS-JNK-CHOP pathway."
09/01/2009 - "Relative concentrations of medicarpin were highest five days post-infection. "
09/01/2009 - "Application of spores induced disease symptoms in the leaves of infected plants and resulted in an increase in the medicarpin precursors formononetin 7-O-glucoside and malonylated formononetin 7-O-glucoside between one and three days post-infection. "
09/01/2000 - "In contrast, elicitation of IOMT-overexpressing plants with CuCl(2) or infecting these plants with Phoma medicaginis leads to greater accumulation of formononetin (4'-O-methyl daidzein) and medicarpin in the leaves than does elicitation or infection of control plants, and no isoformononetin is detected. "
03/01/1992 - "Chickpea (Cicer arietium L.) produces the antimicrobial compounds (phytoalexins) medicarpin and maackiain in response to infection by microorganisms. "
|3.||Wounds and Injuries (Trauma)
11/13/2007 - "The results indicate that the genetic and biochemical mechanisms underlying accumulation of medicarpin differ depending on the nature of the stimulus and suggest a role for MJ as a signal for rapid hydrolysis of preformed, conjugated intermediates for antimicrobial biosynthesis during wound responses."
12/01/2003 - "By in situ staining with diphenylboric acid 2-aminoethyl ester, by thin-layer chromatography, reverse-phase high-performance liquid chromatography, and two-photon laser-scanning microscopy spectrometry, tumor-specific flavones, isoflavones and pterocarpans were detected, namely 7,4'-dihydroxyflavone (DHF), formononetin, and medicarpin. "
12/01/2015 - "We aimed to determine whether medicarpin and millepurpan, two isoflavonoids isolated from alfalfa leaves, may have pro-apoptotic effects against drug-sensitive (P388) and multidrug resistant P388 leukemia cells (P388/DOX). "
12/01/2015 - "Medicarpin and millepurpan, two flavonoids isolated from Medicago sativa, induce apoptosis and overcome multidrug resistance in leukemia P388 cells."
12/01/2015 - "These data indicate that medicarpin and millepurpan possess pro-apoptotic properties and potentiate the cytotoxicity of chemotherapy drugs in multidrug resistant P388 leukemia cells by modulating P-gp-mediated efflux of drugs. "
|7.||NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)
|2.||Drug Therapy (Chemotherapy)