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21-deoxytetrahydroaldosterone

used in diagnosis of primary aldosteronism; RN given refers to (3alpha,5beta,11beta)-isomer

Also Known As:

3,18-dihydroxy-11,18-epoxy-pregnan-20-one

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - Pregnenes: 1
        Pregnenediones
        Aldosterone: 11485
        21-deoxytetrahydroaldosterone: 2
Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Adrenal Cortex Hormones: 62914
    - Hydroxycorticosteroids: 7
      - 11-Hydroxycorticosteroids: 56
        Aldosterone: 11485
        21-deoxytetrahydroaldosterone: 2

Related Diseases

1.	Hyperaldosteronism (Conn Syndrome) 01/01/1985 - "21-Deoxytetrahydroaldosterone excretion in primary hyperaldosteronism." 02/01/1986 - "Radioimmunoassay of urinary 21-deoxytetrahydroaldosterone in primary aldosteronism and 21-hydroxylase deficiency."
2.	Congenital adrenal hyperplasia due to 21 hydroxylase deficiency 02/01/1986 - "Radioimmunoassay of urinary 21-deoxytetrahydroaldosterone in primary aldosteronism and 21-hydroxylase deficiency." 02/01/1986 - "The diminished tetrahydroaldosterone/21-deoxytetrahydroaldosterone ratio found in patients with 21-hydroxylase deficiency may be attributed to increased bacterial conversion of tetrahydroaldosterone to 21-deoxytetrahydroaldosterone but could also stem from a deficiency implicating zona glomerulosa (aldosterone biosynthesis) regardless of the stage and clinical presentation of the disease."

Related Drugs and Biologics

1.	Aldosterone
2.	tetrahydroaldosterone