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butane

Also Known As:
n-butane
Networked: 111 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Lancia, Massimo: 2 articles (12/2015 - 05/2012)
2. Suadoni, Fabio: 2 articles (12/2015 - 05/2012)
3. Perry, Andrew W: 2 articles (09/2014 - 11/2012)
4. Woods, Damith T: 2 articles (09/2014 - 11/2012)
5. Talalay, Paul: 2 articles (09/2013 - 05/2010)
6. Carneiro, José Thiers: 2 articles (12/2012 - 11/2012)
7. Zhang, Y: 2 articles (12/2001 - 06/2000)
8. Monte, Andrew A: 1 article (12/2015)
9. Flaten, Hanna K: 1 article (12/2015)
10. Uchida, Kyoko: 1 article (12/2015)

Related Diseases

1. Asphyxia (Suffocation)
2. Chromosome Aberrations (Chromosome Abnormalities)
06/01/2001 - "These biomarkers included: (1) metabolic genotypes (CYP2E1, EH, GST M1, GST T1, ADH2, ADH3), determined in Prague and Burlington, VT; (2) urinary M1 and M2 metabolites (1,2-dihydroxy-4-[N-acetylcysteinyl]-butane and 1-hydroxy-2-[N-acetylcysteinyl]-3-butene, respectively), determined in Albuquerque, NM and Leiden; (3) hemoglobin adducts (N-[2-dihydroxy-3-butenyl]valine=HBVal and N-[2,3,4-trihydroxybutyl]valine=THBVal), determined in Amsterdam and Chapel Hill, NC, respectively; (4) HPRT mutations determined by autoradiographic assay in Galveston, TX, with slides re-read in Burlington, VT; (6) hypoxanthine-guanine phosphoribosyltransferase (HPRT) mutations determined by cloning assay in Leiden with mutational spectra characterized in Burlington, VT; (7) sister chromatid exchanges and chromosome aberrations determined by standard methods and FISH analysis in Prague. "
03/20/2007 - "The initial study found that urine concentrations of the metabolites 1,2-dihydroxy-4-(acetyl) butane (M1) and 1-dihydroxy-2-(N-acetylcysteinyl)-3-butene (M2) and blood concentrations of the hemoglobin adducts N-[2-hydroxy-3-butenyl] valine (HB-Val) and N-[2,3,4-trihydroxy-butyl] valine (THB-Val) constitute excellent biomarkers of exposure, both being highly correlated with BD exposure levels, and that GST genotypes modulate at least one metabolic pathway, but that irreversible genotoxic effects such as chromosome aberrations and HPRT gene mutations are neither associated with BD exposure levels nor with worker genotypes (GST [glutathione-S-transferase]-M1, GSTT1, CYP2E1 (5' promoter), CYP2E1 (intron 6), EH [epoxide hydrolase] 113, EH139, ADH [alcohol dehydrogenase]2 and ADH3). "
3. Alcoholic Liver Diseases (Alcoholic Liver Disease)
4. Intrahepatic Cholestasis
5. Ameloblastoma

Related Drugs and Biologics

1. Propane
2. Cytochrome P-450 CYP2E1 (CYP2E1)
3. Biological Markers (Surrogate Marker)
4. Valine (L-Valine)
5. S-Adenosylmethionine (Ademetionine)
6. Hypoxanthine Phosphoribosyltransferase (Hypoxanthine Guanine Phosphoribosyltransferase)
7. Hemoglobins (Hemoglobin)
8. Plastics
9. Nitrous Oxide (Laughing Gas)
10. Epoxide Hydrolases

Related Therapies and Procedures

1. Cryosurgery
2. Curettage
3. Resuscitation
4. Intensive Care (Surgical Intensive Care)
5. Decompressive Craniectomy