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1,2,3,4,6,7,8-heptachlorodibenzodioxin

contaminant of pentachlorophenol
Also Known As:
1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin; HCDD; HpCDD
Networked: 39 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Bridoux, Frank: 3 articles (01/2019 - 06/2016)
2. Jaccard, Arnaud: 3 articles (01/2019 - 06/2016)
3. Javaugue, Vincent: 3 articles (01/2019 - 06/2016)
4. Sirac, Christophe: 3 articles (01/2019 - 06/2016)
5. Touchard, Guy: 3 articles (01/2019 - 06/2016)
6. Komatsuda, Atsushi: 2 articles (09/2022 - 07/2017)
7. Arnulf, Bertrand: 2 articles (01/2019 - 06/2016)
8. Bender, Sébastien: 2 articles (01/2019 - 01/2017)
9. Cohen, Camille: 2 articles (01/2019 - 06/2016)
10. Joly, Florent: 2 articles (01/2019 - 06/2016)

Related Diseases

1. Nephrotic Syndrome (Syndrome, Nephrotic)
2. Immunoglobulin Light-chain Amyloidosis
3. Body Weight (Weight, Body)
4. Renal Insufficiency (Renal Failure)
5. Diabetic Nephropathies (Diabetic Nephropathy)
12/01/2013 - "Heavy chain deposition disease (HCDD) is one of three entities of monoclonal immunoglobulin deposition disease, characterized histopathologically by the presence of nodular glomerulosclerosis and glomerular and tubular deposition of monoclonal heavy chains without associated light chains. "
01/01/2017 - "Here we retrospectively studied 15 patients with biopsy-proven HCDD of whom 14 presented with stage 3 or higher chronic kidney disease, with nephrotic syndrome in 9. Renal lesions were characterized by nodular glomerulosclerosis, with linear peritubular and glomerular deposits of γ-heavy chain in 12 patients or α-heavy chain in 3 patients, without concurrent light chain staining. "
01/01/2011 - "In clinical and pathologic terms, LCDD, LHCDD and HCDD display essentially similar characteristics, such as involvement of multiple organs, prominent renal involvement with severe renal failure, diabetes-like nodular glomerulosclerosis, marked thickening of tubular basement membranes, and monotypic deposits of Ig light chains (mostly κ) and/or heavy chains (mostly γ) that feature a non-organized granular, electron-dense appearance by electron microscopy. "
10/01/2012 - "We present a case of HCDD from our archival material, who presented with rapidly progressive renal failure and nephrotic syndrome and was found to have nodular glomerulosclerosis on renal biopsy which on immunofluorescence and electron microscopy confirmed HCDD of immunoglobulin G1 type without any light-chain deposition. "

Related Drugs and Biologics

1. Proteasome Inhibitors
2. Bortezomib (Velcade)
3. Polychlorinated Dibenzodioxins (TCDD)
4. 1,2,3,7,8-pentachlorodibenzo-p-dioxin
5. 1,2,3,6,7,8-hexachlorodibenzodioxin
6. Immunoglobulins (Immunoglobulin)
7. Immunoglobulin G (IgG)
8. 1,2,3,4,6,7,8-heptachlorodibenzodioxin
9. Interleukin-8B Receptors
10. Polyethylene (Polythene)

Related Therapies and Procedures

1. Activities of Daily Living (ADL)