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amyloid enhancing factor

glycoprotein that is distinct from either of the 2 known secondary amyloid proteins, AA or P-component; isolation and molecular characterization have not been performed
Also Known As:
AEF-GP; amyloid enhancing factor (AEF); amyloid enhancing glycoprotein
Networked: 46 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Lidar, Merav: 2 articles (11/2012 - 07/2007)
2. Shtrasburg, Shmuel: 2 articles (11/2012 - 07/2007)
3. Livneh, Avi: 2 articles (11/2012 - 07/2007)
4. Pras, Mordechai: 2 articles (11/2012 - 07/2007)
5. Gal, Rivka: 2 articles (11/2012 - 07/2007)
6. Nyström, Sofia N: 2 articles (09/2012 - 01/2008)
7. Westermark, Gunilla T: 2 articles (09/2012 - 01/2008)
8. Ueda, Mitsuharu: 2 articles (10/2010 - 11/2006)
9. Ando, Yukio: 2 articles (10/2010 - 11/2006)
10. Sun, Xuguo: 2 articles (10/2010 - 11/2006)

Related Diseases

1. Amyloidosis
2. Amyloid Plaque
07/01/1999 - "Although amyloid-enhancing factor is not required, its addition to culture medium results in larger and more numerous amyloid deposits. "
03/28/1995 - "Preincubation of amyloid enhancing factor with IDOX significantly reduced the formation of amyloid deposits. "
10/01/1997 - "Moreover, amyloid deposition in apoE-deficient mice as well as C57BL/6J control mice started 48 or 72 hours after injection of amyloid-enhancing factor and silver nitrate, although the amount of amyloid deposit in C57BL/6J control mice was slightly larger than that in apoE-deficient mice. "
02/01/1994 - "Previous studies into the nature of the relationship between ubiquitin (UB), possessing intrinsic amyloid enhancing factor (AEF) activity; serum amyloid A (SAA), the precursor protein of AA amyloid; and activated monocytoid cells have indicated a temporal and spatial relationship between these proteins and tissue AA amyloid deposits. "
10/01/1997 - "Hepatic mRNA levels of the negative APR apolipoprotein A-I (apo A-I) and serum albumin were down-regulated by silver nitrate treatment; rmIL-1ra partially restored serum albumin mRNA levels but not those of apo A-I. The IL-1ra-mediated reduction in inflammation-induced hepatic mRNA and serum protein concentrations of A-SAA and SAP (the precursors of the main protein components of amyloid deposits in secondary amyloidosis) was, however, not sufficient to prevent or delay early amyloid deposition in the silver nitrate/amyloid enhancing factor model of accelerated amyloidosis. "
3. Inflammation
4. Echinococcosis (Hydatid Cysts)
5. Alzheimer Disease (Alzheimer's Disease)

Related Drugs and Biologics

1. Amyloid (Amyloid Fibrils)
2. Ubiquitin
3. Serum Amyloid A Protein (Serum Amyloid A)
4. Steroids
5. Proteins (Proteins, Gene)
6. Silver Nitrate
7. Caseins (Casein)
8. allogenic effect factor (AEF)
9. Messenger RNA (mRNA)
10. Collagen Type IV (Type IV Collagen)

Related Therapies and Procedures

1. Injections
2. Intravenous Injections
3. Subcutaneous Injections