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MESK

nonionic detergent

Also Known As:

MESK 1

Networked: 6 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- MESK: 6

Experts

1.	Leach, J K: 2 articles (10/2016 - 09/2004)
2.	O'Rear, E A: 2 articles (10/2016 - 09/2004)
3.	Patterson, E: 2 articles (10/2016 - 09/2004)
4.	Leach, J Kent: 2 articles (06/2004 - 01/2004)
5.	O'Rear, Edgar A: 2 articles (06/2004 - 01/2004)
6.	Patterson, Eugene: 2 articles (06/2004 - 01/2004)
7.	Kapur, Suman: 1 article (08/2020)
8.	Mujawdiya, Pavan Kumar: 1 article (08/2020)
9.	Sharad, Shashwat: 1 article (08/2020)
10.	Sharma, Pravesh: 1 article (08/2020)

Related Diseases

1.	Hemorrhage 10/05/2016 - "Compared to free streptokinase, significant improvements in bleeding were observed with MESK as demonstrated by (1) delayed onset of bleeding, (2) shortened duration, and (3) reduction in the volume of lost blood, consistent with less systemic fibrinogen degradation. "
2.	Thrombosis (Thrombus) 09/01/2004 - "MESK demonstrated accelerated flow restoration compared with FREE SK for each condition in plasma (23.8 +/- 4.5% faster) and whole blood clots (17.2 +/- 9.2% faster). " 01/01/2004 - "MESK appears to resist adsorption to the leading edge of the thrombus, a common limitation for the permeation of free plasminogen activators. " 06/01/2004 - "In this study, coronary artery thrombosis was produced in the anesthetized dog by the injection of thrombin + whole blood, and then one of five randomly selected formulations was administered intravenously: saline, blank microcapsules, free streptokinase (FREE SK), streptokinase and blank microcapsules (FREE SK + BLANK), or streptokinase entrapped in polymer microcapsules (MESK). "
3.	Metabolic Syndrome (Dysmetabolic Syndrome X) 08/11/2020 - "Four groups of Swiss albino mice: (1) normal diet (ND), (2) high-fat diet (HFD), (3) HFD + Orlistat (100 µg/kg), and (4) HFD + MESK (75 µg/kg), were used to monitor various biochemical parameters associated with metabolic syndrome (glucose, total cholesterol, triglycerides) and body weight in an eight-week-long study. "
4.	Obesity 08/11/2020 - "This study is designed to evaluate the ability of Mangifera indica seed kernel extract (MESK) in restoring the intestinal barrier and preventing obesity and associated metabolic complications in a high-fat diet-induced obese mouse model. " 08/11/2020 - "Our results, for the first time, establish MESK as a nutraceutical which prevents disruption of the intestinal barrier and thereby intercepts the adverse consequences of compromised intestinal permeability such as obesity, hyperglycemia, dyslipidemia, and systemic inflammation."
5.	Body Weight (Weight, Body) 08/11/2020 - "Interestingly, MESK significantly reduced HFD-induced body weight gain, hepatic lipid accumulation, hepatic fibrosis, hyperglycemia, and dyslipidemia. " 08/11/2020 - "Four groups of Swiss albino mice: (1) normal diet (ND), (2) high-fat diet (HFD), (3) HFD + Orlistat (100 µg/kg), and (4) HFD + MESK (75 µg/kg), were used to monitor various biochemical parameters associated with metabolic syndrome (glucose, total cholesterol, triglycerides) and body weight in an eight-week-long study. "

Related Drugs and Biologics

1.	Streptokinase
2.	Fibrinogen (Factor I)
3.	Triglycerides (Triacylglycerol)
4.	Thrombin
5.	Polymers
6.	Glucose (Dextrose)
7.	Cholesterol
8.	Capsules (Microcapsules)
9.	Orlistat (Xenical)
10.	Plasminogen Activators (Plasminogen Activator)