bis(perfluoro-n-hexyl)-1,2-ethylene

structure given in first source; RN given refers to cpd without isomeric designation

Also Known As:

F-66E; bis(perfluoro-n-hexyl)-1,2-ethylene, (E)-isomer; bis(perfluoro-n-hexyl)-1,2-ethylene, (Z)-isomer; bis(perfluorohexyl)ethylene

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Halogenated Hydrocarbons: 42
    - Fluorinated Hydrocarbons: 4
      - Fluorocarbons: 1209
        bis(perfluoro-n-hexyl)-1,2-ethylene: 2

Related Diseases

1.	Neoplasms (Cancer) 05/01/1989 - "The rate of tumor take and the period before detection of tumors were not modified when an emulsion of F-66E was injected simultaneously or 10 days after 3LL cells. " 05/01/1989 - "Tumor bearing mice were pretreated with 15 ml/kg of F-66E emulsion (50 w/v%) or PFOB (100 w/v%) emulsion in the presence of carbogen for 1 hr prior to and during irradiation. " 05/01/1989 - "The effects of two new perfluorochemical emulsions based on F-66E and PFOB which carry, in combination with carbogen, more oxygen than Fluosol-DA 20% were investigated on a human tumor xenograft (HRT18). "
2.	Lewis Lung Carcinoma 05/01/1989 - "The effects of two new concentrated perfluorochemical emulsions based on F-66E and PFOB, which carry significantly more oxygen than Fluosol-DA 20%, were tested on normal tissues (toxicity and radiation response) and on the development of metastases from Lewis Lung Carcinoma (3LL) in female C57 BL/6 mice. "
3.	Splenomegaly 05/01/1989 - "Splenomegaly already observed in 3LL bearing mice was significantly increased by F-66E emulsion injection. "
4.	Neoplasm Metastasis (Metastasis) 05/01/1989 - "Mean survival of mice, and the number of metastases on lung surfaces were similar in F-66E injected mice and control mice." 05/01/1989 - "The effects of two new concentrated perfluorochemical emulsions based on F-66E and PFOB, which carry significantly more oxygen than Fluosol-DA 20%, were tested on normal tissues (toxicity and radiation response) and on the development of metastases from Lewis Lung Carcinoma (3LL) in female C57 BL/6 mice. "
5.	Body Weight (Weight, Body) 05/01/1989 - "Twenty one days after injection of F-66E or PFOB emulsions (15 ml/kg body weight), the spleen and liver weights were significantly increased but had returned to normal after 2-3 months. "

Related Drugs and Biologics

1.	Oxygen (Dioxygen)
2.	Emulsions
3.	yolk phospholipids drug combination salts pluronic F-68 perfluorotripropylamine perfluorodecalin hydroxyethyl starch glycerol glucose
4.	perflubron (L 1913)
5.	carbogen