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griseolic acid

from Streptomyces griseoaurantiacus SANK 63479; structure given in first source

Also Known As:

alpha-L-talo-Oct-4-enofuranuronic acid, 1-(6-amino-9H-purin-9-yl)-3,6-anhydro-6-C-carboxy-1,5-dideoxy-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        Adenosine: 12431
        griseolic acid: 1
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - Adenosine: 12431
      - griseolic acid: 1
  - Ribonucleosides: 49
    - Adenosine: 12431
      - griseolic acid: 1

Related Diseases

1.

08/01/1991 - "These results suggest that multipolar-type cell shape change in Neuro-2a cells is correlated with the accumulation of intracellular cyclic AMP and that griseolic acid is a useful compound to induce neuroblastoma cells into terminal differentiation."
08/01/1991 - "The morphological change of several neuroblastoma cell lines induced by griseolic acid, a novel and potent inhibitor of cyclic nucleotide phosphodiesterase (PDE), was examined. "
08/01/1991 - "Multiple neurite formation in neuroblastoma cell lines by griseolic acid, a potent inhibitor of cyclic nucleotide phosphodiesterases."

Related Drugs and Biologics

1.	Phosphoric Diester Hydrolases (Phosphodiesterases)
2.	Cyclic Nucleotides
3.	Cyclic AMP (AMP, Cyclic)