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malate dehydrogenase- (oxaloacetate- decarboxylating) (NAD+)

decarboxylates malate in presence of NAD+ to form pyruvate & carbon dioxide & NADH; also decarboxylates added oxaloacetate

Also Known As:

NAD-malic enzyme

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Alcohol Oxidoreductases: 56
      - NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases
        Malate Dehydrogenase: 346
        malate dehydrogenase-(oxaloacetate-decarboxylating) (NAD+): 2

Related Diseases

1.	Tetraploidy 06/01/1987 - "Photosynthetic gas exchange, activities of six key C(4) cycle enzymes, amounts of soluble protein, chlorophyll, and DNA, and various leaf anatomical and structural features were measured in naturally occurring tetraploid and octaploid plants of the NAD-malic enzyme type C(4) grass Panicum virgatum L. "
2.	Starvation 08/01/1989 - "When Brassica nigra leaf petiole suspension cells were subjected to 7 days of inorganic phosphate (Pi) starvation the extractable activity of: (a) pyrophosphate:fructose 6-phosphate 1-phosphotransferase, nonphosphorylating NADP-glyceraldehyde 3-phosphate dehydrogenase, phosphoenolpyruvate phosphatase, and phosphoenolpyruvate carboxylase increased at least fivefold, (b) phosphorylating NAD-glyceraldehyde 3-phosphate dehydrogenase decreased about sixfold, and (c) ATP:fructose 6-phosphate 1-phosphotransferase, 3-phosphoglycerate kinase, pyruvate kinase, or NAD malic enzyme was not altered. "

Related Drugs and Biologics

1.	Suspensions
2.	Pyruvate Kinase
3.	Proteins (Proteins, Gene)
4.	Phosphotransferases (Kinase)
5.	Phosphoenolpyruvate Carboxylase
6.	Phosphates (Orthophosphate)
7.	Oxidoreductases (Dehydrogenase)
8.	NADP (NADPH)
9.	NAD (NADH)
10.	Glyceraldehyde 3-Phosphate (Glyceraldehyde 3 Phosphate)