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liver antigen LA-1

MW 67,000-80,000; its presence in serum denotes non-specific liver injury; do not confuse with LA-1, an HSV-2 oncogene protein
Also Known As:
soluble liver antigen
Networked: 64 relevant articles (2 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Czaja, Albert J: 8 articles (01/2012 - 02/2002)
2. Lohse, Ansgar W: 5 articles (07/2010 - 02/2002)
3. Vergani, Diego: 4 articles (04/2014 - 03/2002)
4. Ballot, Eric: 4 articles (06/2012 - 09/2002)
5. Johanet, Catherine: 4 articles (06/2012 - 09/2002)
6. Norman, Gary L: 4 articles (01/2012 - 12/2002)
7. Shums, Zakera: 4 articles (01/2012 - 12/2002)
8. Herkel, Johannes: 4 articles (07/2010 - 02/2002)
9. Lohse, A W: 4 articles (09/2006 - 04/2000)
10. Bogdanos, Dimitrios P: 3 articles (02/2015 - 03/2002)

Related Diseases

1. Autoimmune Hepatitis
2. Liver Diseases (Liver Disease)
3. Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
01/01/1994 - "Antibodies directed against soluble liver antigen (SLA), liver kidney microsomal antigen (LKM-1-AG), and antimitochondrial antigen M2 (M2-AMA) are critical serological markers for the differential diagnosis of autoimmune chronic active hepatitis (AI-CAH) and primary biliary cirrhosis (PBC). "
07/01/1989 - "No patient developed autoantibodies specifically associated with autoimmune liver diseases such as liver kidney microsomal antibodies, autoantibodies to soluble liver antigen and the primary biliary cirrhosis specific subtypes of antimitochondrial antibodies. "
01/01/2005 - "Antibodies to soluble liver antigen/liver pancreas, asialoglycoprotein receptor, actin, liver cytosol type 1, nuclear antigens specific to primary biliary cirrhosis, and pore complex antigens constitute an investigational repertoire that promises to have prognostic and diagnostic value. "
08/01/2010 - "Antibodies to soluble liver antigen, actin, liver cytosol type 1, asialoglycoprotein receptor, chromatin, cyclic citrullinated peptide, and uridine glucuronosyltransferases have been associated with the occurrence, severity, and progression of autoimmune hepatitis, and antibodies to Sp100, gp210, and centromere have had similar implications in primary biliary cirrhosis. "
12/01/2009 - "Sera from 281 patients with chronic cholestatic conditions, including primary biliary cirrhosis (PBC), primary sclerosing cholangitis, AMA-positive autoimmune hepatitis, and "undetermined cholangiopathy" were tested for the following PBC-associated autoantibodies: anti-gp210, anti-sp100, conventional anti-M2, anti-M2 (MIT3) IgG, anti-M2 (MIT3) IgA, as well as anti-centromere, anti-soluble liver antigen, and anti-chromatin. "
4. Liver Failure
5. Disease Susceptibility (Diathesis)

Related Drugs and Biologics

1. Antibodies
2. Primary sclerosing cholangitis
3. Budesonide (Pulmicort)
4. Cyclosporine (Ciclosporin)
5. mycophenolate mofetil (Cellcept)
6. Antigens
7. HLA-DRB1 antigen (HLA DRB1)
8. Peptides
9. Autoantibodies
10. Antinuclear Antibodies

Related Therapies and Procedures

1. Liver Transplantation