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Miraxid
combination of above cpds; used in treatment of respiratory infections
Also Known As:
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((aminophenylacetyl)amino)-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (2S-(2alpha,5alpha,6beta(S*)))-, mixt. with (2S-(2alpha,5alpha,6beta))-(2,2-dimethyl-1-oxopropoxy)
Networked:
6
relevant articles (
2
outcomes,
2
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Lactams: 2198
beta-Lactams: 2386
Penicillins: 16651
Penicillin G: 1462
Ampicillin: 4218
Pivampicillin: 101
Miraxid: 6
Amdinocillin: 128
Amdinocillin Pivoxil: 190
Miraxid: 6
Sulfur Compounds: 278
beta-Lactams: 2386
Penicillins: 16651
Penicillin G: 1462
Ampicillin: 4218
Pivampicillin: 101
Miraxid: 6
Amdinocillin: 128
Amdinocillin Pivoxil: 190
Miraxid: 6
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
beta-Lactams: 2386
Penicillins: 16651
Penicillin G: 1462
Ampicillin: 4218
Pivampicillin: 101
Miraxid: 6
Amdinocillin: 128
Amdinocillin Pivoxil: 190
Miraxid: 6
Experts
1.
De Guia, Blanca
: 1 article (09/2010)
2.
Dowswell, Therese
: 1 article (09/2010)
3.
Festin, Mario R
: 1 article (09/2010)
4.
Guinto, Valerie T
: 1 article (09/2010)
Related Diseases
1.
Respiratory Tract Infections (Respiratory Tract Infection)
01/01/1985 - "
Miraxid given twice daily for respiratory tract infections is as effective as Deteclo but causes significantly fewer side-effects.
"
01/01/1985 - "
A multi-centre general practice clinical evaluation of pivmecillinam plus pivampicillin ('Miraxid') and co-trimoxazole ('Septrin') in respiratory tract infections.
"
01/01/1985 - "
A clinical comparison of pivmecillinam plus pivampicillin (Miraxid) and a triple tetracycline combination (Deteclo) in respiratory infections treated in general practice.
"
01/01/1986 - "
A comparative study of Miraxid (pivmecillinam plus pivampicillin) and Augmentin (amoxycillin plus clavulanic acid) in the treatment of lower respiratory tract infections in general practice.
"
01/01/1985 - "
Seven-day courses of either pivmecillinam 200 mg plus pivampicillin 250 mg (Miraxid) or a combination of tetracycline hydrochloride, chlortetracycline hydrochloride and demeclocycline hydrochloride (Deteclo) 300 mg, both given twice daily, were compared in a multicentre general practice study in 408 patients with symptoms of upper or lower respiratory tract infection.
"
2.
Infections
01/01/1985 - "
Assessment at 7 days showed no difference in clinical efficacy between the two treatments where 193 of the 208 infections receiving Miraxid (93%) were rated as either cured or improved compared with 181 of the 201 infections treated with Deteclo (90%).
"
3.
Bronchitis
01/01/1986 - "
Both treatments were equally effective, with 99 (71%) patients with acute bronchitis being successfully treated with Miraxid and 107 (74%) with Augmentin.
"
01/01/1986 - "
Patients with acute bronchitis (140 on Miraxid, 144 on Augmentin) received a 7-day course of treatment and those with acute exacerbations of chronic bronchitis (55 on Miraxid, 49 on Augmentin) a 10-day course of treatment.
"
01/01/1986 - "
Two treatments, pivmecillinam 200 mg plus pivampicillin 250 mg (Miraxid) given twice-daily and amoxycillin 250 mg plus clavulanic acid 125 mg (Augmentin) given three times daily were compared in two parallel groups of 388 general practice patients with acute bronchitis or acute exacerbations of chronic bronchitis.
"
4.
Chronic Bronchitis
01/01/1986 - "
In acute exacerbations of chronic bronchitis, Miraxid was successful in 29 (53%) patients and Augmentin in 24 (49%) patients.
"
01/01/1986 - "
Patients with acute bronchitis (140 on Miraxid, 144 on Augmentin) received a 7-day course of treatment and those with acute exacerbations of chronic bronchitis (55 on Miraxid, 49 on Augmentin) a 10-day course of treatment.
"
01/01/1983 - "
Double-blind comparison of pivmecillinam plus pivampicillin ('Miraxid') with pivampicillin alone in chronic bronchitis: a Danish multi-centre study.
"
01/01/1986 - "
Two treatments, pivmecillinam 200 mg plus pivampicillin 250 mg (Miraxid) given twice-daily and amoxycillin 250 mg plus clavulanic acid 125 mg (Augmentin) given three times daily were compared in two parallel groups of 388 general practice patients with acute bronchitis or acute exacerbations of chronic bronchitis.
"
5.
Pyelonephritis
02/20/1991 - "
[Miraxid not a first choice agent in acute pyelonephritis].
"
Related Drugs and Biologics
1.
deteclo
2.
Amoxicillin-Potassium Clavulanate Combination (Co-amoxiclav)
3.
Pivampicillin
4.
Amdinocillin Pivoxil (Pivmecillinam)
5.
Tetracycline (Achromycin)
6.
Demeclocycline (Declomycin)
7.
Chlortetracycline (Aureomycin)
8.
Clavulanic Acid (Potassium Clavulanate)
9.
Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)
10.
Cephalexin (Cefalexin)