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1-aminooxy-3-aminopropane

polyamine biosyn inhibitor; structure given in first source

Also Known As:

3-aminooxy-1-propanamine; 1-Propanamine, 3-(aminooxy)-

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Propylamines: 1
    - 1-aminooxy-3-aminopropane: 2

Experts

1.	Khomutov, Maxim A: 1 article (02/2010)
2.	Kochetkov, Sergey N: 1 article (02/2010)
3.	Madhubala, Rentala: 1 article (02/2010)
4.	Mandal, Swati: 1 article (02/2010)
5.	Saxena, Neiha: 1 article (02/2010)
6.	Simonian, Alina R: 1 article (02/2010)
7.	Vepsalainen, Jouko: 1 article (02/2010)
8.	Weisell, Janne: 1 article (02/2010)

Related Diseases

1.	Leukemia 07/31/1985 - "1-Aminooxy-3-aminopropane at 0.5 mM concentration inhibited the growth of HL-60 promyelocytic leukemia cells and this inhibition was prevented by spermidine but not by putrescine."
2.	Visceral Leishmaniasis (Kala Azar) 02/01/2010 - " inhibitory effect of one of the newly synthesized compound, 1-guanidinooxy-3-aminopropane (GAPA), was compared with that of well-known inhibitors of ornithine decarboxylase namely, alpha-difluoromethylornithine (DFMO) and 1-aminooxy-3-aminopropane (APA) on Leishmania donovani, a protozoan parasite that causes visceral leishmaniasis. "

Related Drugs and Biologics

1.	Spermidine
2.	Putrescine
3.	Ornithine Decarboxylase (Decarboxylase, Ornithine)
4.	Eflornithine (Ornidyl)