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Bio-Gel P-4

polyacrylamide gel; see also record for polyacrylamide gels

Networked: 10 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Janczarek, M: 1 article (07/2011)
2.	Kamińska, T: 1 article (07/2011)
3.	Kutkowska, J: 1 article (07/2011)
4.	Paduch, R: 1 article (07/2011)
5.	Turska-Szewczuk, A: 1 article (07/2011)
6.	Urbanik-Sypniewska, T: 1 article (07/2011)

Related Diseases

1.	Neoplasms (Cancer) 07/01/2011 - "A polysaccharide obtained by gel chromatography on Bio-Gel P-4 of the high molecular mass material from Rt120 had a toxic effect on tumor HeLa cells but was inactive against the normal human skin fibroblast cell line. " 01/25/1989 - "The ability of Ehrlich tumor cell alpha(1,3)-galactosyltransferase to catalyze the incorporation of alpha-D-Gal residues into a specific branch of bi-, tri-, and tetraantennary oligosaccharides has been investigated by acetolysis followed by gel filtration of the fragments on Bio-Gel P-4. " 04/01/1982 - "The presence of immunoreactive bombesin in a human lung small-cell carcinoma grown in nude mice was established by several criteria: (i) Radioimmunoassay of tissue extracts for bombesin revealed approximately 6.5 pmol/g of tissue; (ii) bombesin was found in 12-14% of the tumor cells by immunohistochemical localization; (iii) gel filtration of small-cell carcinoma extract on Sephadex G-75 and Bio-Gel P-4 gave only a single peak of immunoreactivity, which occurred at the elution volume of bombesin; and (iv) reverse-phase HPLC of acid-solubilized extracts separated the immunoreactive material into three discrete peaks, one of which eluted with a retention time identical to that of synthetic bombesin. "
2.	Mucolipidoses (Sialidosis) 01/01/1986 - "The TCA soluble, labeled, material from the sialidosis and the control fibroblasts was separated, isolated and purified on AG1-X8, QAE Sephadex A-25 and Bio-Gel P-4 chromatography columns. " 12/16/1991 - "Urinary oligosaccharides of galactosialidosis and sialidosis patients were investigated by the Bio-Gel P-4 column chromatography in order to delineate each clinical subtype biochemically. "
3.	Melanoma (Melanoma, Malignant) 06/01/1996 - "The glycosylation of tissue plasminogen activator (t-PA) obtained from the Bowes melanoma cell line was re-examined using methods of serial lectin affinity chromatography coupled with Bio-Gel P-4 gel filtration chromatography and exoglycosidase sequencing. " 10/01/1991 - "The N-linked sugar chains of melanoma cell membrane from five murine B16 melanoma clones (F1, F10, BL6, W1-4, and C4-1) with different degrees of metastatic abilities after intravenous and intrafootpad injections were released quantitatively as oligosaccharides by hydrazinolysis, and their structures were analyzed by serial lectin column chromatography, Bio-Gel P-4 column chromatography, and sequential glycosidase digestion. "
4.	Mannosidase Deficiency Diseases (Mannosidosis) 06/10/1980 - "Nine oligosaccharide fractions were purified from the urine of mannosidosis patients by Bio-Gel P-4 column chromatography, paper chromatography, and paper electrophoresis. "
5.	Small Cell Carcinoma 04/01/1982 - "The presence of immunoreactive bombesin in a human lung small-cell carcinoma grown in nude mice was established by several criteria: (i) Radioimmunoassay of tissue extracts for bombesin revealed approximately 6.5 pmol/g of tissue; (ii) bombesin was found in 12-14% of the tumor cells by immunohistochemical localization; (iii) gel filtration of small-cell carcinoma extract on Sephadex G-75 and Bio-Gel P-4 gave only a single peak of immunoreactivity, which occurred at the elution volume of bombesin; and (iv) reverse-phase HPLC of acid-solubilized extracts separated the immunoreactive material into three discrete peaks, one of which eluted with a retention time identical to that of synthetic bombesin. "

Related Drugs and Biologics

1.	Oligosaccharides
2.	Lectins
3.	Glycoside Hydrolases (Endoglycosidases)
4.	Sugars
5.	sephadex
6.	Transferrins
7.	Tissue Extracts
8.	Polysaccharides (Glycans)
9.	Tissue Plasminogen Activator (Alteplase)
10.	Bombesin

Related Therapies and Procedures

1.	Injections