2-norbornene

11/25/2022 - "The norbornene scaffold has arisen as a promising structure in medicinal chemistry due to its possible therapeutic application in cancer treatment. "
11/25/2022 - "Norbornene and Related Structures as Scaffolds in the Search for New Cancer Treatments."
11/25/2022 - "In addition, the use of norbornene, and its related compounds, encapsulation in nanosystems for its use in cancer therapies is here detailed."
11/14/2014 - "The complete chemical and biological properties of the new norbornene-based polymeric nanocarrier, intended for combination cancer chemotherapy, are discussed. "
01/01/2018 - "Tetrazine and norbornene terminals are grafted on EcN and PMTOS/PMDOX copolymers, respectively, and the mild and site-specific bioorthogonal reaction between them maintains the viability, motion ability, and tumor accumulation capability of the conjugated EcN. "

11/27/2023 - "Here we developed two novel biomaterial formulations of granular hydrogels for tissue regeneration after stroke: highly porous microgels (i.e., Cryo microgels) and microgels loaded with heparin-norbornene nanoparticles with covalently bound SDF-1α. "
07/05/2023 - "Here we developed 2 novel biomaterials for tissue regeneration after stroke, a highly porous granular hydrogel termed Cryo microgels, and heparin-norbornene nanoparticles with covalently bound SDF-1α. "

03/01/1978 - "Synthesis of and allergic contact dermatitis to bicyclo-[2,2,1]-heptyl-alpha-methylene-gamma-butyrolactones derived from norbornene and camphene."

11/01/2021 - "Wound dressings under the form of films constituted of modified alginate (methacrylated alginate - AlgMA) versus a gelatine derivative containing norbornene functionalities (GelNB) are developed and evaluated for their moisturizing effects, followed by further in vivo testing to assay their wound healing potential. "

01/01/2023 - "Efficient MePTDO copolymerizations with norbornene-based monomers are demonstrated, including a norbornenyl monomer functionalized with a peptide substrate for inflammation-associated matrix metalloproteinases (MMPs). "