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mitomycin A

RN given refers to (1aS-(1aalpha,8beta,8aalpha,8balpha))-isomer; structure given in first source

Also Known As:

mitomycin A, (1aS-(1aalpha,8alpha,8aalpha,8balpha))-isomer; mitomycin B

Networked: 13 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Quinones: 434
  - Indolequinones: 12
    - Mitomycins: 11
      - mitomycin A: 13
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azirines
    - Mitomycins: 11
      - mitomycin A: 13
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Indolequinones: 12
        Mitomycins: 11
        mitomycin A: 13

Experts

1.	Altaf, Faryal: 1 article (03/2022)
2.	Kandhi, Sameer: 1 article (03/2022)
3.	Khaja, Misbahuddin: 1 article (03/2022)
4.	Qureshi, Zaheer A: 1 article (03/2022)
5.	Yapor, Laura: 1 article (03/2022)
6.	Hupe, Marie Christine: 1 article (02/2021)
7.	Kramer, Mario: 1 article (02/2021)
8.	Matzen, Merle: 1 article (02/2021)
9.	Merseburger, Axel S: 1 article (02/2021)
10.	Offermann, Anne: 1 article (02/2021)

Related Diseases

1.	Lung Neoplasms (Lung Cancer) 06/01/1987 - "In order to compare the antitumor effect of bleomycin (BLM) administered by continuous subcutaneous infusion (CSI) with that of BLM given by intravenous infusion (IVI), 34 patients with lung cancer metastatic from the cervix were entered into this study after being treated with a combination of bleomycin and mitomycin (B-M). "
2.	Bronchogenic Carcinoma 06/01/1985 - "Treatment of non-small cell bronchogenic carcinoma with vinblastine and mitomycin: a Southwest Oncology Group Study."
3.	Neoplasms (Cancer) 05/01/2006 - "The effect of repeat transurethral resection on recurrence and progression rates in patients with T1 tumors of the bladder who received intravesical mitomycin: a prospective, randomized clinical trial." 11/01/2002 - "Streptoverticillum caespitosus ATCC27422 is a producing strain of mitomycin A for cancer therapy. " 05/01/1992 - "Experimental tumor inhibitory and toxic properties of the mitomycin A analogue 7-(2-hydroxyethoxy) mitosane (BMY-25551)." 03/01/2022 - "Mitomycin, a widely used chemotherapeutic agent for gastrointestinal (GI) cancers anal and breast cancers, has been reported to occasionally cause severe TTP and hemolytic uremic syndrome (HUS) cases. "
4.	Leukemia P388 07/01/1991 - "These correlations are in contrast to those made in the P388 leukemia assay in mice wherein the most active mitomycin C and mitomycin A analogues were the most hydrophilic ones. " 06/01/1977 - "Mitomycin A, mitomycin C, and N-methylmitomycin A were active against P388 leukemia in mice."
5.	Cardiotoxicity 01/01/1992 - "Cardiotoxicity of mitomycin A, mitomycin C, and seven N7 analogs in vitro."

Related Drugs and Biologics

1.	Vinblastine (Vinblastine Sulfate)
2.	Bleomycin (Blenoxane)
3.	Mitomycin (Mitomycin-C)
4.	Gemcitabine
5.	mitosane
6.	N-methylmitomycin A
7.	thiamine triphosphorate (TTP)

Related Therapies and Procedures

1.	Subcutaneous Infusions
2.	Intravenous Infusions
3.	Therapeutics
4.	Combination Drug Therapy (Combination Chemotherapy)