|1.||Huang, Yuan: 7 articles (10/2015 - 09/2003)|
|2.||Hennink, Wim E: 5 articles (08/2015 - 03/2008)|
|3.||van Nostrum, Cornelus F: 4 articles (08/2015 - 10/2010)|
|4.||Storm, Gert: 4 articles (07/2011 - 03/2008)|
|5.||Zhou, Zhou: 3 articles (10/2015 - 03/2012)|
|6.||Rijcken, Cristianne J F: 3 articles (07/2011 - 10/2010)|
|7.||Talelli, Marina: 3 articles (07/2011 - 10/2010)|
|8.||Lammers, Twan: 3 articles (07/2011 - 10/2010)|
|9.||Ulbrich, Karel: 3 articles (03/2011 - 10/2009)|
|10.||Wang, Dong: 2 articles (01/2016 - 02/2014)|
06/01/2007 - "To study a non-invasive method of using contrast enhanced magnetic resonance imaging (MRI) to visualize the real-time pharmacokinetics, biodistribution and tumor accumulation of paramagnetically labeled poly[N-(2-hydroxypropyl)methacrylamide] (PHPMA) copolymer conjugates with different molecular weights and spacers in tumor-bearing mice. "
01/01/2012 - "Semitelechelic (ST) poly[N-(2-hydroxypropyl)methacrylamide]-TRZ conjugates are successfully synthesized and evaluated as a potential drug delivery system that actively targets Her2-overexpressing cancer cells. "
06/01/2007 - "Noninvasive visualization of pharmacokinetics, biodistribution and tumor targeting of poly[N-(2-hydroxypropyl)methacrylamide] in mice using contrast enhanced MRI."
01/01/2003 - "We investigated to what extent passive accumulation and retention of hydroxypropyl methacrylamide copolymer of CPT (pHPMA-CPT) in tumors and modulation of the drug release influence efficacy. "
10/01/2015 - "Improvement of anti-tumor abilities on human non-small cell lung carcinoma by micellization and cross-linking of N-(2-hydroxypropyl) methacrylamide copolymers."
03/01/2012 - "The aim of this study was to develop a G3-C12-mediated drug delivery system based on N-(2-hydroxypropyl) methacrylamide (HPMA) copolymers targeting to Gal-3-expressed human PC-3 prostate carcinoma cells. "
09/01/1996 - "Combination chemotherapy and photodynamic therapy with N-(2-hydroxypropyl) methacrylamide copolymer-bound anticancer drugs inhibit human ovarian carcinoma heterotransplanted in nude mice."
07/01/1999 - "Cooperativity between free and N-(2-hydroxypropyl) methacrylamide copolymer bound adriamycin and meso-chlorin e6 monoethylene diamine induced photodynamic therapy in human epithelial ovarian carcinoma in vitro."
07/01/1999 - "The purpose of this study was to determine the interaction between free (unbound) and N-(2-hydroxypropyl) methacrylamide (HPMA) copolymer bound adriamycin and meso-chlorin e6 monoethylene diamine (Mce6) induced photodynamic therapy in combination in their cytotoxic activities against human ovarian epithelial carcinoma (OVCAR-3) in vitro. "
09/01/1996 - "This study characterizes the efficacy and toxicity of: (a) free Adriamycin and N-(2-hydroxypropyl) methacrylamide (HPMA) copolymer-Adriamycin conjugate (P-A); (b) free and HPMA copolymer-meso-chlorin e6 monoethylene diamine disodium salt (Mce6) conjugate (P-C) and light-induced photodynamic therapy; and (c) combinations of the HPMA copolymer conjugates (P-A and P-C) in the destruction of human epithelial ovarian carcinoma heterotransplanted in the nude mouse (OVCAR-3). "
|3.||Ovarian Neoplasms (Ovarian Cancer)
03/01/2008 - "A series of cationic, methacrylamide polymers was tested for use as a biodegradable gene carrier in ovarian cancer. "
03/01/2008 - "Biodegradable, cationic methacrylamide-based polymers for gene delivery to ovarian cancer cells in mice."
06/01/2014 - "In this study, gelatine methacrylamide (GelMA)-based hydrogels were characterized and established as in vitro and in vivo spheroid-based models for ovarian cancer, reflecting the advanced disease stage of patients, with accumulation of multicellular spheroids in the tumour fluid (ascites). "
03/01/2008 - "Tumor transfection activity of polyplexes consisting of a reporter gene and different methacrylamide polymers was assessed, after intraperitoneal injection in mice bearing an ovarian cancer xenograft. "
|4.||Colonic Neoplasms (Colon Cancer)
05/21/2009 - "As we are currently developing dextrin- and semi-telechelic poly[N-(2-hydroxypropyl)methacrylamide] (ST-HPMA)-protein conjugates as new therapeutics, the aim of this study was to examine the effect of polymer on activity, autolysis and its thermal stability using trypsin conjugates as a model and compare to the data obtained for mPEG conjugates. "
|2.||Integrin beta3 (GPIIIa)
|3.||monomethoxypolyethylene glycol (MPEG)
|5.||Ethylene Glycol (Monoethylene Glycol)
|8.||Epidermal Growth Factor Receptor (EGF Receptor)
|1.||Photochemotherapy (Photodynamic Therapy)
|4.||Heterologous Transplantation (Xenotransplantation)