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scleroglucan

Networked: 8 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Macromolecular Substances: 97
- Polymers: 13051
  - Biopolymers: 773
    - Glucans: 1624
      - scleroglucan: 8
Carbohydrates: 22023
- Polysaccharides: 15383
  - Glucans: 1624
    - scleroglucan: 8

Experts

1.	Adams, Gary G: 1 article (04/2020)
2.	Ballance, Simon: 1 article (04/2020)
3.	Harding, Stephen E: 1 article (04/2020)
4.	Li, Xinxin: 1 article (04/2020)
5.	Lu, Yudong: 1 article (04/2020)
6.	Wolf, Bettina: 1 article (04/2020)
7.	Zobel, Hanne: 1 article (04/2020)
8.	Bimczok, Diane: 1 article (02/2009)
9.	Rau, Udo: 1 article (02/2009)
10.	Rothkötter, Hermann-Josef: 1 article (02/2009)

Related Diseases

1.	Communicable Diseases (Infectious Diseases) 02/01/2009 - "Therefore, scleroglucan molecules of low molecular weight are able to induce activation and maturation of porcine DC, which are key initiators of inflammatory and adaptive immune responses, and could provide improved protection against infectious diseases."
2.	Infections 01/01/1988 - "Intramuscular or intravenous administration of PSAT before infection of mice by the attenuated RH strain, resulted in a significant enhancement of survival: 100% of survival in the treated group, compared to 33% in controls and 50% in mice pretreated with Scleroglucan (10 mg/kg, intravenously). " 03/01/1997 - "The natural and semisynthetic carbohydrates scleroglucan, locust bean gum, tamarind gum (glyloid) and its three sulphate derivatives (GP4311, GP4327 and GP4324), glycogen and its two sulphate derivatives (GP4427 and GP4435), alginic acid and dextran sulphate, were investigated for their inhibitory effect on rubella virus (RV) infection of Vero cells. "
3.	Bites and Stings (Sting) 01/20/2023 - "Cyclic dinucleotide (CDN) STING agonists, such as cAIMP, diABZI, and 2',3'-cGAMP, and Dectin-1 agonist scleroglucan, demonstrated the most potent, broad-spectrum antiviral function. " 01/01/2023 - "STING agonists (cAIMP, diABZI, and 2',3'-cGAMP) and Dectin-1 agonist scleroglucan demonstrate the most potent, broad-spectrum antiviral function. "
4.	Neoplasms (Cancer) 04/01/1991 - "Scleroglucan (250 mg/kg, intravenously) stimulated in vivo murine macrophage phagocytic activity (66%, P less than .001) and increased in vitro macrophage tumor cytotoxicity against syngeneic tumor targets by 124% (P less than .05). "
5.	Melanoma (Melanoma, Malignant) 04/01/1991 - "Scleroglucan therapy increased survival of mice challenged with syngeneic lymphoma, melanoma or adenocarcinoma. "

Related Drugs and Biologics

1.	Polysaccharides (Glycans)
2.	Glucans
3.	Antiviral Agents (Antivirals)
4.	dectin 1
5.	Dextran Sulfate
6.	Zymosan
7.	Inulin
8.	Glycogen
9.	Dextrans (Dextran)
10.	Carbohydrates

Related Therapies and Procedures

1.	Intravenous Administration
2.	Therapeutics