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TZU 0460

RN given refers to HCl; structure given in first source

Also Known As:

HOE 760; HOE-760; N-(3-(3-(N(1)-piperidinylmethyl)phenoxy)propyl)acetoxyacetamide; TZU-0460

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - TZU 0460: 3

Related Diseases

1.	Renal Insufficiency (Renal Failure) 01/01/1986 - "Dosage adjustment of TZU-0460 is necessary in renal failure."
2.	Stomach Ulcer (Gastric Ulcer) 01/01/1985 - "TZU-0460 was about twice as active as cimetidine on these experimental models of gastric ulcers. " 01/01/1985 - "TZU-0460, given p.o., prevented the formation of gastric ulcers induced by exposure to stress, pylorus-ligation, both pylorus-ligation and acetylsalicyclic acid, indometacin or reserpine in rats. "
3.	Pneumonia (Pneumonitis) 01/01/1986 - "[Effects of TZU-0460, a new histamine H2-receptor blocker, on the prophylaxis of acid aspiration pneumonitis and its placental transfer]."
4.	Duodenal Ulcer (Curling's Ulcer) 01/01/1985 - "TZU-0460, given p.o., prevented the formation of duodenal ulcer induced by cysteamine in rats, whereas cimetidine failed to prevent it significantly."

Related Drugs and Biologics

1.	Acids
2.	Reserpine (Serpasil)
3.	Indomethacin (Indometacin)
4.	Histamine (Histamine Dihydrochloride)
5.	Cysteamine (Mercaptamine)
6.	Cimetidine (Biomet)

Related Therapies and Procedures

1.	Ligation