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Also Known As:
BAY o 1248; BAY-o 1248; BAY-o-1248; N-(beta-(4-ethoxycarbonyl)phenoxy)ethyl-1-desoxy-nojirimycin; N-(beta-(4-ethoxycarbonyl)phenoxy)ethyl-1-desoxynojirimycin
relevant articles (
Bio-Agent Context: Research Results
Organic Chemicals: 58
Imino Sugars: 22
Heterocyclic Compounds: 60
1-Ring Heterocyclic Compounds
Imino Sugars: 22
08/01/1986 - "
BAY-O-1248 led to a significant reduction in daily food intake and weight gain in rats fed Diet A but not Diet B.
08/01/1997 - "
When hearts were perfused with 1 mM BAY o 1248, added before ischemia, glycogenolysis was inhibited in the three groups and functional recovery was hampered in both the control and lactate groups.
01/01/1987 - "
Bay o 1248 is a potent alpha-glycosidase inhibitor that reduces postprandial hyperglycemia when administered p.o.
Type 2 Diabetes Mellitus (MODY)
04/04/1987 - "
In a placebo-controlled double-blind randomised group comparison, the tolerability and metabolic effect of emiglitate, a new second-generation alpha-glucosidase inhibitor, was evaluated in 10 Indians with non-insulin-dependent diabetes mellitus being treated with sulphonylureas.
Body Weight (Weight, Body)
12/01/1986 - "
Rats fed a standard diet containing Bay o 1248 over 10 days consumed less food, gained about 30% less body weight than controls and showed meteorism.
Related Drugs and Biologics
alpha-Glucosidases (Acid Maltase)
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