WR 33278

symmetrical disulfide of WR-1065

Also Known As:

N1,N1'-(Disulfanediyldi-2,1-ethanediyl)di(1,3-propanediamine); WR-33278; WR33278; 1,3-Propanediamine, N,N''-(dithiodi-2,1-ethanediyl)bis-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Drug-Related Side Effects and Adverse Reactions 06/01/2000 - "From the extent of the increase in insoluble protein in the nucleus, protein denaturation by WR-1065 is expected to contribute to drug toxicity at concentrations greater than approximately 4 mM. WR-33278, the disulfide form of WR-1065, was approximately twice as effective as the free thiol at denaturing nuclear proteins. "

1.	Sulfhydryl Compounds (Thiols)
2.	Proteins (Proteins, Gene)
3.	Nuclear Proteins (Protein, Nuclear)
4.	Disulfides
5.	N-(2-mercaptoethyl)-1,3-diaminopropane