cefcanel daloxate (KY 109)

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4 relevant articles (2 outcomes, 2 trials/studies) found for this Bio-Agent

Description: pro-drug to improve oral absorption of KY-087; structure given in first source

Also Known As:

KY 109; (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl-7(O-(alanyl)mandelamido)-3-((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl-3-cephem-4-carboxylate hydrochloride; KY-109; L-Alanine, 2-((2-(((5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy)carbonyl)-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-7-yl)amino)-2-oxo-1-phenylethyl ester, monohydrochloride, (6R-(6alpha,7beta(R*)))-

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 40

Polycyclic Compounds: 58

Bridged Compounds: 2

Bicyclo Compounds

Heterocyclic Bicyclo Compounds

Related Diseases

1.	Urinary Tract Infections (Urinary Tract Infection) 01/01/1993 - "The clinical and bacteriologic efficacy of 3 days of cefcanel daloxate therapy, compared with 3 days of amoxicillin for the treatment of acute uncomplicated urinary tract infection was compared in a prospective randomized double-blind multicentre study" 01/01/1993 - "These data suggest that cefcanel daloxate and amoxicillin are comparable as regards efficacy and adverse effects for 3-day therapy of acute uncomplicated urinary tract infection" Order ALL the reference details at left...
2.	Infection 07/01/1988 - "The therapeutic efficacy of KY-109 against experimental intraperitoneal infections caused by Gram-positive and Gram-negative organisms in mice was comparable to that of CEX but inferior to that of CCL" 07/01/1988 - "In experimental granuloma pouch models in rats and kidney infection in rabbits, therapeutic efficacy of KY-109 was either comparable or superior to that of CEX and CCL." Order ALL the reference details at left...
3.	Granuloma 07/01/1988 - "In experimental granuloma pouch models in rats and kidney infection in rabbits, therapeutic efficacy of KY-109 was either comparable or superior to that of CEX and CCL." Order ALL the reference details at left...
4.	Renal Insufficiency 02/01/1994 - "The present study investigated the pharmacokinetics of cefcanel following a single oral dose of cefcanel daloxate hydrochloride 300 mg to healthy volunteers and to patients with various degrees of stable renal insufficiency" Order ALL the reference details at left...
5.	Maxillary Sinusitis 06/01/1995 - "A new oral prodrug cephalosporin, cefcanel daloxate, was compared with cefaclor, another oral cephalosporin, in the treatment of acute purulent maxillary sinusitis" Order ALL the reference details at left...

Related Drugs and Biologics

1.	Amoxicillin (Wymox)
2.	cefcanel
3.	Cefaclor (Ceclor)

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