cyclic 3',5'-uridine monophosphate

10/01/2023 - "In bacteria, cCMP and cUMP have a key role in defense against infection with bacterial viruses. "
01/01/2018 - "aeruginosa carrier of the exoY-plasmid produced high levels of cUMP and caused the most severe course of infection. "
05/15/2015 - "cUMP also appeared in serum, urine and faeces following infection. "
05/15/2015 - "Intratracheal infection of mice with recombinant Pseudomonas aeruginosa harboring the nucleotidyl cyclase toxin ExoY massively increased cUMP in lung. "
11/11/2021 - "We discovered a family of bacterial pyrimidine cyclase enzymes that specifically synthesize cCMP and cUMP following phage infection and demonstrate that these molecules activate immune effectors that execute an antiviral response. "

05/30/2014 - "Intact HEK293 cells and B103 neuroblastoma cells possess high basal concentrations of the established second messengers cAMP and cGMP and of the emerging second messengers cCMP and cUMP. "
09/05/2014 - "Human HEK293 cells and rat B103 neuroblastoma cells are of neuronal origin and possess high basal concentrations of cCMP and cUMP that can be attributed to soluble adenylyl cyclase activity. "

01/01/2017 - "cCMP induced PKA-independent apoptosis via the intrinsic and ER-stress pathway in S49 mouse lymphoma cells, and cCMP as well as cUMP induced apoptosis in human HEL cells via the intrinsic pathway. "
01/01/2020 - "The effects of 100 μM of 3',5'-cGMP, cAMP, cCMP, and cUMP as well as of the corresponding membrane-permeant acetoxymethyl esters on anti-CD3-antibody (OKT3)-induced IL-2 production of HuT-78 cutaneous T cell lymphoma (Sézary lymphoma) cells were analyzed. "

01/01/2022 - "The medical-psychological emergency units (CUMP) have the specific mission of taking care of people suffering from psychological trauma following a collective catastrophic event. "
06/14/2021 - "Medical-psychological emergency units (Cellules d'Urgence Médico-Psychologiques, CUMP) are deployed following major events where there is a risk of psychological trauma, in order to provide acute and proper psychological care for the victims. "

01/01/2020 - "The effects of 100 μM of 3',5'-cGMP, cAMP, cCMP, and cUMP as well as of the corresponding membrane-permeant acetoxymethyl esters on anti-CD3-antibody (OKT3)-induced IL-2 production of HuT-78 cutaneous T cell lymphoma (Sézary lymphoma) cells were analyzed. "