|1.||Park, Jongsun: 4 articles (03/2014 - 01/2009)|
|2.||Li, Yuwen: 3 articles (03/2014 - 01/2009)|
|3.||Yang, Keum-Jin: 3 articles (03/2014 - 01/2009)|
|4.||Hur, Gang Min: 3 articles (03/2014 - 01/2009)|
|5.||Park, Kyeong Ah: 3 articles (03/2014 - 01/2009)|
|6.||Hemmings, Brian A: 3 articles (05/2009 - 01/2009)|
|7.||Cho, M-H: 2 articles (03/2013 - 12/2007)|
|8.||Chung, Y-S: 2 articles (03/2013 - 12/2007)|
|9.||Cho, Myung-Haing: 2 articles (05/2012 - 06/2009)|
|10.||Beck, George R: 2 articles (05/2012 - 06/2009)|
|1.||Lung Neoplasms (Lung Cancer)
06/15/2009 - "In this study, we addressed this question by studying the effects of lentivirus-based CTMP in the lungs of 9- and 13-week-old K-ras(LA1) mice, a model of lung cancer. "
05/01/2012 - "Our data suggest that CTMP may therefore play a critical role in mitochondrial-mediated apoptosis in lung cancer cells."
06/15/2009 - "The effects of CTMP on lung cancer progression and Akt-related signals were evaluated. "
06/15/2009 - "An aerosol of lentivirus-based CTMP was delivered into 9- and 13-week-old K-ras(LA1) mice, a model of lung cancer, through a nose-only inhalation system twice a week for 4 weeks. "
12/01/2007 - "Our results emphasize the importance of noninvasive-targeted delivery of CTMP for lung cancer therapy in the future. "
05/01/2012 - "Carboxyl-terminal modulator protein (CTMP), a novel Akt binding partner, prevents Akt activation at the plasma membrane in response to various stimuli, and thus possesses a tumor suppressor-like function. "
06/15/2009 - "Long-term repeated viral delivery of CTMP may provide a useful tool for designing lung tumor treatment."
06/15/2009 - "Long-term repeated delivery of CTMP effectively reduced tumor progression in the lungs at different stages of development. "
01/01/2009 - "Carboxyl-terminal modulator protein (CTMP) has been identified as a novel PKB binding partner in a yeast two-hybrid screen, and appears to be a negative PKB regulator with tumor suppressor-like properties. "
07/06/2007 - "However, a nuclear pool of CTMP was detectable in HPDE-E6E7 cells that showed a dynamic concentrated expression pattern, a feature that further distinguished HPDE-E637 cells from cancer cells. "
03/01/2014 - "The involvement of CTMP and LETM1 in PI3K/PKB signaling was investigated in HEK293 cells by transient transfection and adenovirus-mediated infection. "
02/15/2011 - "Thus, metabolizing FFAs and TNF by moderate daily exercise with dietary control improves innate immune responses to infection in DIO mice via restoration of CTMP and chromatin modification."
12/01/2002 - "In patients with a polymerase chain reaction proven (n = 324) Ct infection, 75%, 70% and 68% were positive for IgG and 45%, 38% and 47%, positive for IgA as determined by the CtMp, CtL and CtS respectively. "
|5.||Glioblastoma (Glioblastoma Multiforme)
03/17/2004 - "Thus, epigenetic downregulation of CTMP transcription is a common aberration in glioblastomas."
03/17/2004 - "Because loss of CTMP function and/or expression may remove the inhibitory effects on Akt and promote tumorigenesis, we studied 93 primary glioblastomas and nine glioblastoma cell lines for CTMP deletion, mutation, promoter hypermethylation, and mRNA expression. "
03/17/2004 - "However, CTMP mRNA expression was lower by at least 50% relative to non-neoplastic brain tissue in 37 (40%) glioblastomas and six (67%) glioma cell lines. "
10/01/2005 - "Glioblastomas frequently carry genetic alterations resulting in an aberrant activation of the phosphoinositol-3-kinase (Pi3k)/protein kinase B (Akt) signalling pathway, including most notably phosphatase and tensin homolog (PTEN) mutation, epidermal growth factor receptor (EGFR) amplification and rearrangement, as well as carboxyl-terminal modulator protein (CTMP) hypermethylation [Knobbe et al., (2004) Hypermethylation and transcriptional downregulation of the carboxyl-terminal modulator protein gene in glioblastomas. "
|1.||Proto-Oncogene Proteins c-akt (Protein Kinase B)
|2.||Small Interfering RNA (siRNA)
|3.||Immunoglobulin G (IgG)
|4.||Histone Deacetylase Inhibitors
|5.||Messenger RNA (mRNA)
|6.||Epidermal Growth Factor Receptor (EGF Receptor)
|7.||Proteins (Proteins, Gene)
|8.||Protein Kinases (Protein Kinase)
|1.||Homologous Transplantation (Allograft)