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5-hydroxy-3',4',6,7-tetramethoxyflavone

isolated from Artemisia argyi

Also Known As:

HTMF

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        5-hydroxy-3',4',6,7-tetramethoxyflavone: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        5-hydroxy-3',4',6,7-tetramethoxyflavone: 2

Experts

1.	Kadalmani, B: 1 article (06/2018)
2.	Kanimozhi, V: 1 article (06/2018)
3.	Palanivel, K: 1 article (06/2018)
4.	Srinivasan, P: 1 article (06/2018)
5.	Sudha, A: 1 article (06/2018)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 06/01/2018 - "Overall, this study brings up scientific evidence for the efficacy of HTMF against MCF-7 breast cancer cells." 06/01/2018 - "The aim of this study was to find the efficacy of 5-hydroxy 3',4',7-trimethoxyflavone (HTMF), a flavonoid compound isolated from the medicinal plant Lippia nodiflora, in inhibiting the proliferation and inducing apoptosis in human breast cancer cell line MCF-7. "
2.	Neoplasms (Cancer) 06/01/2018 - "In silico molecular docking and dynamics studies with MDM2-p53 protein revealed that HTMF was more potent compound that could inhibit the binding of MDM2 with p53 and, therefore, could trigger apoptosis in cancer cell. " 12/01/2022 - "Four known compounds with cytotoxic effects on cancer cell lines were isolated from the most active fraction, including 5-Hydroxy-3',4',6,7-tetramethoxyflavone (eupatilin 7-methyl ether), 5-hydroxy 3,3',4',6,7-pentamethoxy-flavone (artemetin), 6-methoxy-7-hydroxycoumarin (scopoletin), and methyl caffeate. "

Related Drugs and Biologics

1.	Flavonoids
2.	3',4',7-trimethoxyflavone
3.	Proteins (Proteins, Gene)
4.	Scopoletin
5.	Ether (Diethyl Ether)
6.	artemetin
7.	eupatilin
8.	methyl caffeate