schisanhenol

a dibenzyl cyclooctane from kernels of Schisandra rubriflora; structure given in first source

Also Known As:

Dibenzo(a,c)cycloocten-1-ol, 5,6,7,8-tetrahydro-2,3,10,11,12-pentamethoxy-6,7-dimethyl-, (6S,7R)-

Networked: 6 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- schisanhenol: 6
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Cyclooctanes: 4
        schisanhenol: 6

Experts

1.	Chen, Cheng-Zhen: 1 article (11/2021)
2.	Gao, Yan: 1 article (11/2021)
3.	Jiang, Hao: 1 article (11/2021)
4.	Kim, Nam-Hyung: 1 article (11/2021)
5.	Li, Ze: 1 article (11/2021)
6.	Liang, Shuang: 1 article (11/2021)
7.	Peng, Yan-Xia: 1 article (11/2021)
8.	Yu, Wen-Jie: 1 article (11/2021)
9.	Yuan, Bao: 1 article (11/2021)
10.	Zhang, Jia-Bao: 1 article (11/2021)

Related Diseases

1.	Wounds and Injuries (Trauma) 01/01/1998 - "[Protective effects of schisanhenol, salvianolic acid A and SY-L on oxidative stress induced injuries of cerebral cells and their mechanisms]." 07/01/2023 - "Results from this present study reveal that Schisanhenol has a potential therapeutic effect on preventing oxLDL-induced endothelial injuries."
2.	Cognitive Dysfunction 02/01/2019 - "The aim of the present study was to evaluate the effect of Schisanhenol on the cognitive impairment induced by scopolamine. " 02/01/2019 - "Intraperitoneal administration of Schisanhenol (10, 30 or 100 mg/kg) significantly attenuated scopolamine-induced cognitive impairment in water morris maze. " 02/01/2019 - "Our findings indicated that Schisanhenol can attenuate scopolamine-induced learning impairment and enhance cognitive function, the mechanism via improve the cholinergic system and antioxidant ability, activate SIRT1-PGC1α signaling, inhibit the phosphorylation of Tau, and would be an effective candidate against cognitive disorders, such as Alzheimer's disease."
3.	Obesity 11/01/2021 - "Schisanhenol (SAL), a biphenyl cyclooctene-type lignin compound which can be extracted and isolated from many plants of the Schisandra family, exhibits a variety of biological activities including anti chronic cough, night sweating, thirst, diabetes, and obesity. "
4.	Neoplasms (Cancer) 07/15/1991 - "Schisanhenol (Sal) did not diminish the antitumor activity of adriamycin in mice bearing P388 ascites tumor. "
5.	Liver Cirrhosis (Hepatic Cirrhosis) 06/01/2020 - "Remarkably, schisanhenol may be a potential anti-liver fibrosis drug and warrants further research." 06/01/2020 - "All these findings suggested that schisanhenol may ameliorate liver fibrosis by inhibiting the transforming growth factor β (TGF-β)/Smad and mitogen-activated protein kinase (MAPK) signaling pathways. "

Related Drugs and Biologics

1.	salvianolic acid A
2.	Therapeutic Uses
3.	Scopolamine (Hyoscine)
4.	oxidized low density lipoprotein
5.	Mitogen-Activated Protein Kinases
6.	Cholinergic Agents (Cholinergics)
7.	Transforming Growth Factors (Transforming Growth Factor)
8.	Lignin
9.	Doxorubicin (Adriamycin)
10.	Antioxidants