TEI 5103 (TG 51)

structure given in first source

Also Known As:

TG 51; 3-(4-(trans-4-aminomethylcyclohexylcarbonyl)phenyl)propionic acid hydrochloride; TEI-5103; TG-51; Benzenepropanoic acid, 4-((4-(aminomethyl)cyclohexyl)carbonyl)-, hydrochloride, trans-

Networked: 9 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phenylpropionates
      - TEI 5103: 9

Experts

1.	Ding, George X: 1 article (09/2021)

Related Diseases

1.	Ulcer 01/01/1992 - "A sensitive and specific radioimmunoassay for a new anti-ulcer drug TG-51 has been developed and applied to the evaluation of its pharmacokinetics in humans. " 01/01/1992 - "Development of radioimmunoassay for TG-51, a new anti-ulcer drug, and its application." 11/01/1987 - "In conclusion, TEI-5103, when given orally, distributes in the gastric mucosa as a target issue directly from the lumen; and only the oral and gastric route of administration lead to the anti-ulcer effect." 11/01/1987 - "These results suggest that the presence of TEI-5103 in the stomach is necessary to elicit its anti-ulcer effect. " 11/01/1987 - "The results indicate that TEI-5103 increases GMBF by acting directly on the gastric microcirculation and that this increasing effect may contribute to the anti-ulcer activity of TEI-5103."
2.	Prediabetic State (Prediabetes) 11/05/2022 - "After adjustment for body mass index (BMI), triacylglycerol/high-density lipoprotein (TG/HDL) ratio and the presence of prediabetes, triacylglycerol (TG) 12:0_18:2_22:6, TG 16:0_11:1_18:2, TG 49:0, TG 51:1 and diacylglycerol (DG) 18:2_22:6 were independently associated with increased T2D risk, whereas lyso-phosphatidylcholine (LPC) O-16:0, LPC P-16:0, LPC O-18:0 and LPC 18:1 were independently associated with decreased T2D risk. "
3.	Peptic Ulcer (Peptic Ulcers) 01/01/1985 - "These results indicate that TEI-5103 is effective as an anti-ulcer agent increasing gastric mucosal blood flow and possibly promoting the healing process of peptic ulcers."
4.	Dementia (Dementias) 01/01/2022 - "Notably, L-proline, L-cystine, ADMA, and N1-acetylspermidine were significantly changed in MCR-only, and PC(40:3), SM(32:1), TG(51:3), eicosanoic acid(20:1), methyl-D-galactoside and TG(50:3) contributed most to the prediction model for MCR-III. Pre-dementia syndrome of MCR has distinct metabolic subtypes, and SCCs and SG may cause different metabolic changes to develop MCR."
5.	Burns 09/01/2021 - "For electron dosimetry, both the AAPM TG-51 and IAEA TRS-398 recommend the use of two formulas developed by Burns et al [Med. Phys. "

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