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ornoprostil
RN given refers to (11alpha,13E,15R,17S)-isomer
Also Known As:
17,20-dimethyl-6-oxo-PGE1 Me ester; 17,20-dimethyl-6-oxo-prostaglandin E1 methyl ester; OU-1308; ornoprostil, (11alpha,13E,15S,17S)-isomer
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Lipids: 114793
Fatty Acids: 27405
Unsaturated Fatty Acids: 8236
Eicosanoids: 3262
Prostaglandins: 17100
Prostaglandins E: 2673
Alprostadil: 3107
ornoprostil: 4
Monounsaturated Fatty Acids: 676
Alprostadil: 3107
ornoprostil: 4
Biological Factors: 2472
Inflammation Mediators: 1113
Autacoids: 276
Eicosanoids: 3262
Prostaglandins: 17100
Prostaglandins E: 2673
Alprostadil: 3107
ornoprostil: 4
Related Diseases
1.
Hemorrhage
01/01/1991 - "
Hyperemia and hemorrhage in the mucosa were also significantly less (p less than 0.05) in the subjects given ornoprostil pretreatment.
"
09/01/1992 - "
Discontinuance of NSAIDs in combination with administration of ornoprostil (prostaglandin E1-derivative), sucralfate, and sulfasalazine put an end to the intestinal bleeding.
"
2.
Peripheral Vascular Diseases (Peripheral Vascular Disease)
07/01/1992 - "
Diligence in the development of native PGs and their structural analogs for human therapy resulted in the following six drugs now being on the market in Japan: PGF2 alpha as the first drug of PGs in the world which induces labor; PGE2 as an orally active labor inducing drug; PGE1 for the treatment of peripheral vascular diseases; gemeprost for therapeutic abortion in the middle-term; ornoprostil, as an oral anti-ulcer agent; limaprost for the treatment of peripheral vascular diseases as an oral agent.
"
3.
Ulcer
07/01/1992 - "
Diligence in the development of native PGs and their structural analogs for human therapy resulted in the following six drugs now being on the market in Japan: PGF2 alpha as the first drug of PGs in the world which induces labor; PGE2 as an orally active labor inducing drug; PGE1 for the treatment of peripheral vascular diseases; gemeprost for therapeutic abortion in the middle-term; ornoprostil, as an oral anti-ulcer agent; limaprost for the treatment of peripheral vascular diseases as an oral agent.
"
4.
Hyperemia
01/01/1991 - "
Hyperemia and hemorrhage in the mucosa were also significantly less (p less than 0.05) in the subjects given ornoprostil pretreatment.
"
5.
Duodenal Ulcer (Curling's Ulcer)
01/01/1990 - "
On the other hand, ornoprostil produced a potent and significant inhibition against ethanol/HCl-induced lesions (greater than 1 microgram/kg), but had no effect on mepirizole-induced duodenal ulcers.
"
Related Drugs and Biologics
1.
Dinoprost
2.
Dinoprostone (PGE2)
3.
Sucralfate (Carafate)
4.
Sulfasalazine (Azulfidine)
5.
Epirizole
6.
Non-Steroidal Anti-Inflammatory Agents (NSAIDs)
7.
Alprostadil (Muse)
8.
Ethanol (Ethyl Alcohol)
9.
limaprost
10.
gemeprost
Related Therapies and Procedures
1.
Therapeutics
2.
Therapeutic Abortion