|1.||Pandey, Siyaram: 12 articles (06/2012 - 01/2005)|
|2.||McNulty, James: 10 articles (06/2012 - 01/2005)|
|3.||Griffin, Carly: 6 articles (06/2011 - 07/2005)|
|4.||Hudlicky, Tomas: 4 articles (06/2012 - 12/2002)|
|5.||Ma, Dennis: 3 articles (06/2012 - 01/2011)|
|6.||Collins, Jonathan: 3 articles (06/2012 - 01/2011)|
|7.||Pettit, George R: 3 articles (04/2012 - 12/2002)|
|8.||Tremblay, Phillip: 2 articles (06/2012 - 01/2011)|
|9.||Mahngar, Kevinjeet: 2 articles (06/2012 - 01/2011)|
|10.||Kekre, Natasha: 2 articles (07/2005 - 01/2005)|
01/01/2010 - "Our results show that pancratistatin is an effective and selective anti-cancer agent with potential for advancement to clinical trials."
01/01/2005 - "Pancratistatin induced apoptosis in all the cancer cell lines used in this study at sub-micromolar concentrations. "
01/01/2005 - "The objective in the present study was to elucidate the mechanism of the anti-neoplastic action of pancratistatin and evaluate the specificity of this compound for cancer cells. "
06/01/2012 - "The natural compound pancratistatin (PST), isolated from the Hymenocallis littoralis plant, specifically induces apoptosis in many cancer cell lines. "
01/01/2012 - "We have reported selective induction of apoptosis in cancer cells by the natural compound pancratistatin (PST). "
|2.||Prostatic Neoplasms (Prostate Cancer)
06/01/2011 - "Our results highlight the potential of pancratistatin for clinical development as a selective therapeutic for treatment of metastatic prostate cancer."
06/01/2011 - "This study presents the novel finding that pancratistatin treatment caused decreased migration capacity and increased autophagy levels in metastatic prostate cancer cells. "
06/01/2011 - "In this study we report, for the first time, the effects of pancratistatin (PST) on models of metastatic prostate cancer. "
06/01/2011 - "Pancratistatin treatment reduced cell viability and induced apoptosis in androgen-responsive (LNCaP) and androgen-refractory (DU145) prostate cancer cell lines in a dose- and time-dependent manner, but with an insignificant effect on normal human fibroblast (NHF) cells at the effective dose. "
06/01/2011 - "The effects of pancratistatin on prostate cancer DU145 and LNCaP cell lines was assessed by microscopy, enzymatic activity assays and Western blotting. "
|3.||Melanoma (Melanoma, Malignant)
02/01/2011 - "The objective of this study was to determine the efficacy of the natural compound pancratistatin (PST), isolated from the Hymenocallis littoralis, in human melanoma cells. "
02/01/2011 - "Sensitization of human melanoma cells by tamoxifen to apoptosis induction by pancratistatin, a nongenotoxic natural compound."
01/01/2010 - "In this ex vivo study, we evaluated the effect of pancratistatin on peripheral blood mononuclear cells obtained from 15 leukemia patients prior to clinical intervention of newly diagnosed patients, as well as others of different ages in relapse and at various disease progression states. "
|2.||DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)
|4.||DNA (Deoxyribonucleic Acid)
|6.||Caspase 3 (Caspase-3)
|7.||Reactive Oxygen Species (Oxygen Radicals)
|10.||Etoposide (VP 16)
|1.||Heterologous Transplantation (Xenotransplantation)