|1.||Kuttan, Ramadasan: 1 article (01/2010)|
|2.||Firdous, Alikunjhi P: 1 article (01/2010)|
|3.||Ramnath, Viswanathan: 1 article (01/2010)|
|4.||Sindhu, Edakkadath R: 1 article (01/2010)|
|5.||Lilienthal, Hellmuth: 1 article (12/2007)|
|6.||Darnerud, Per Ola: 1 article (12/2007)|
|7.||Molin, Ylva: 1 article (12/2007)|
|8.||Blomberg, Jonas: 1 article (12/2007)|
|9.||Lundgren, Magnus: 1 article (12/2007)|
|10.||Ilbäck, Nils-Gunnar: 1 article (12/2007)|
12/05/2007 - "In the present study coxsackievirus B3 (CVB3) adapted to Balb/c mice was used to examine whether infection affects xenobiotic-metabolising CYP1A1 and CYP2B gene expression (measured by RT-PCR) and the corresponding enzyme activities of ethoxyresorufin-O-deethylase (EROD) and pentoxyresorufin-O-depentylase (PROD), as observed on day 3 of infection. "
04/01/1993 - "In hepatic microsomes from uninduced mice, cytochrome P450 levels and the rates of dealkylation of ethoxyresorufin, benzyloxyresorufin, pentoxyresorufin, and aminopyrine were significantly reduced, by 40-60%, after 48 hr of infection. "
|2.||Body Weight (Weight, Body)
05/01/1993 - "Following a single dose of DAS (200 mg/kg body weight, ig), liver microsomal pentoxyresorufin dealkylase (PORd) activity, a representative activity of P450 2B1, was induced 3-, 16-, 26-, and 43-fold at 6, 12, 18, and 24 h after the treatment, respectively. "
02/01/2007 - "Both myclobutanil and triadimefon significantly induced pentoxyresorufin O-depentylase activities at their MTD levels: myclobutanil, 8.1-fold at 150mgkg(-1) body weight day- ; and triadimefon, 18.5-fold at 115mgkg(-1) body weight day-'. "
08/01/1997 - "Dams receiving BHT at a nominal dose of 500 mg/kg body weight/day showed liver enlargement accompained by induction of pentoxyresorufin O-depentylase and glutathione S-transferase, and proliferation of the endoplasmic reticulum. "
02/15/2005 - "Propiconazole significantly induced both pentoxyresorufin O-dealkylation (PROD) and methoxyresorufin O-dealkylation (MROD) activities in both rat and mouse liver at the 150 mg/kg body weight/day and 75 mg/kg body weight/day doses. "
12/01/1987 - "The activities of aniline hydroxylase, benzo[a]pyrene hydroxylase, aminopyrine-N-demethylase, ethoxyresorufin-O-deethylase, and pentoxyresorufin-O-depentylase were increased 2-3-fold, 12-15-fold, 1.4-1.8-fold, 20-24-fold, and 6-8-fold, respectively, on gestation day 18, when a single dose of PBCO (5-10 mL/kg body weight, p.o.) had been administered 24 h earlier. "
|3.||Hepatocellular Carcinoma (Hepatoma)
01/30/1998 - "Sodium fluoride activated the phase I ethoxyresorufin-O-deethylase (to 240%) and pentoxyresorufin-O-depentylase (to 156%), and the phase II glutathione transferase to 120% of the basal activities in rat hepatoma-derived Fa32 cells. "
01/01/2010 - "Using specific resorufin derivatives as substrates in vitro, the concentration of meso-zeaxanthin needed for 50 % inhibition of CYP1A2 (7-methoxyresorufin-O-demethylase) was 5 µg/ml, for CYP2B 1/2 (7- pentoxyresorufin-O-depentylase) was 8 µg/ml and for CYP1A1 (7-ethoxyresorufin-O-deethylase) was 12 µg/ml, while that of CYP 2E1 (aniline hydroxylase) was 7µg/ml and for CYP 1A, 2A, 2B, 2D and 3A (aminopyrene-N-demethylase) was 10.5 µg/ml. Evaluated using nitroso diethyl amine (NDEA) induced hepatocellular carcinoma in rats, treatment with meso-zeaxanthin reduced the tumor incidence when compared to the control group. "
|1.||Cytochrome P-450 CYP1A1 (CYP1A1)
|2.||Cytochrome P-450 CYP2B1 (PROD)
|3.||Cytochrome P-450 Enzyme System (Cytochrome P450)
|4.||Glutathione Transferase (Glutathione S-Transferase)
|8.||Cytochrome P-450 CYP2E1 (CYP2E1)
|9.||Cytochrome P-450 CYP1A2 (CYP1A2)
|10.||Cytochromes b5 (Cytochrome b5)