cyclohexanecarboxylic acid

RN given refers to parent cpd

Also Known As:

cyclohexanecarboxylic acid, calcium salt; cyclohexanecarboxylic acid, cobalt salt; cyclohexanecarboxylic acid, lead salt; cyclohexanecarboxylic acid, potassium salt; cyclohexanecarboxylic acid, sodium salt; cyclohexanecarboxylic acid, sodium salt, 11C-labeled

Networked: 12 relevant articles (2 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Alicyclic Hydrocarbons: 1
      - Cycloparaffins: 6
        Cyclohexanes: 3
        Cyclohexanecarboxylic Acids
        cyclohexanecarboxylic acid: 12
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Cyclohexanecarboxylic Acids
      - cyclohexanecarboxylic acid: 12

Experts

1.	Linden, Joel: 3 articles (11/2006 - 05/2002)
2.	Matsumoto, Keiko: 2 articles (01/2013 - 12/2009)
3.	Taira, Tomoe: 2 articles (01/2013 - 12/2009)
4.	Takashi, Tohru: 2 articles (01/2013 - 12/2009)
5.	Takayama, Gensuke: 2 articles (01/2013 - 12/2009)
6.	Yokoyama, Mika: 2 articles (01/2013 - 12/2009)
7.	Kern, John A: 2 articles (04/2005 - 05/2002)
8.	Kron, Irving L: 2 articles (04/2005 - 05/2002)
9.	Laubach, Victor E: 2 articles (04/2005 - 05/2002)
10.	Tribble, Curtis G: 2 articles (04/2005 - 05/2002)

Related Diseases

1.	Melanosis (Freckles) 12/01/2010 - "The purpose of this study was to assess the efficacy of a formulation containing a combination of trans-4-(aminomethyl) cyclohexanecarboxylic acid/potassium azeloyl diglycinate/niacinamide compared with an emulsion-based control in the treatment of melasma in Thai adults. " 12/01/2010 - "Effects of trans-4-(aminomethyl) cyclohexanecarboxylic acid/potassium azeloyl diglycinate/niacinamide topical emulsion in Thai adults with melasma: a single-center, randomized, double-blind, controlled study."
2.	Asthma (Bronchial Asthma) 12/24/2009 - "Consequently, our efforts have led to the discovery of trans-4-[1-[[2,5-dichloro-4-(1-methyl-3-indolylcarboxamido)phenyl]acetyl]-(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid (14e) with potent activity (IC(50) = 5.4 nM) and significantly improved bioavailability in rats, dogs, and monkeys (100%, 91%, 68%), which demonstrated excellent oral efficacy in murine and guinea pig models of asthma. "
3.	Pneumonia (Pneumonitis) 04/01/2005 - "Previous studies have shown that ATL-146e (4-{3-[6-amino-9-(5-ethylcarbamoyl-3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-yl]-prop-2-ynyl}-cyclohexanecarboxylic acid methyl ester), a selective adenosine A2A receptor agonist, reduces lung inflammation after ischemia-reperfusion. "
4.	Ischemia 04/01/2005 - "Previous studies have shown that ATL-146e (4-{3-[6-amino-9-(5-ethylcarbamoyl-3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-yl]-prop-2-ynyl}-cyclohexanecarboxylic acid methyl ester), a selective adenosine A2A receptor agonist, reduces lung inflammation after ischemia-reperfusion. "
5.	Reperfusion Injury 11/27/2006 - "Liver reperfusion injury is reduced by lymphocyte depletion or activation of adenosine A2A receptors (A2ARs) with the selective agonist 4-{3-[6-amino-9-(5-ethylcarbamoyl-3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-yl]- prop-2-ynyl}-cyclohexanecarboxylic acid methyl ester (ATL146e). " 10/01/2001 - "The adenosine A2A agonist ATL-146e (4-[3-[6-Amino-9-(5-ethylcarbamoyl-3,4-dihydroxytetrahydro-furan-2-yl)-9H-purin-2-yl]-prop-2-ynyl]-cyclohexanecarboxylic acid methyl ester) has been shown to prevent reperfusion injury in multiple organ systems through inhibition of activated leukocyte-endothelial interaction. "

Related Drugs and Biologics

1.	Niacinamide (Nicotinamide)
2.	Emulsions
3.	azeloglycine
4.	Esters
5.	furan
6.	ATL 146e
7.	Adenosine A2A Receptor (Adenosine A2A Receptors)
8.	Antigens
9.	Adenosine (Adenocard)
10.	Cyclooxygenase 2 (Cyclooxygenase-2)