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5- hydroxy- N- (2- piperidinylmethyl)- 2- (2,2,2- trifluoroethoxy)benzamide (MODF)

metabolite of flecainide; structure given in first source

Also Known As:

MODF; S 24623; S-24623

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - Flecainide: 1248
      - 5-hydroxy-N-(2-piperidinylmethyl)-2-(2,2,2-trifluoroethoxy)benzamide: 4

Experts

1.	Andreae, Michael H: 1 article (03/2022)
2.	Baer, Blake: 1 article (03/2022)
3.	Boateng, Henry: 1 article (03/2022)
4.	Chinchilli, Vernon M: 1 article (03/2022)
5.	Jardine, Kayla: 1 article (03/2022)
6.	Mun, Frederick: 1 article (03/2022)
7.	Pradhan, Sandeep: 1 article (03/2022)
8.	Ringenbach, Kathy: 1 article (03/2022)
9.	Cai, Zhen-jie: 1 article (09/2006)
10.	Chen, Wen-sheng: 1 article (09/2006)

Related Diseases

1.	Wounds and Injuries (Trauma) 03/01/2022 - "Deceased patients had a significantly greater age, ISS, vasopressor usage, ICU stay, incidence of MODF, incidence of genitourinary disease, anticoagulant usage, ventilator usage, number of orthopaedic surgeries, and orthopaedic injuries. "
2.	Urogenital Diseases 03/01/2022 - "Deceased patients had a significantly greater age, ISS, vasopressor usage, ICU stay, incidence of MODF, incidence of genitourinary disease, anticoagulant usage, ventilator usage, number of orthopaedic surgeries, and orthopaedic injuries. "
3.	Renal Insufficiency (Renal Failure) 09/15/2006 - "And the reasons were low cardiac output syndrome, arrhythmia, multiple organ dysfunction failure (MODF) and renal failure. "
4.	Starvation 01/01/1985 - "Investigations of eight of these double mutants showed that modE and modF mutations suppress the inhibitory action of modD and modG on production of hyphal cell derivatives and on growth renewal.-Taken together these results lead to the suggestion that the accomplishment of a quiescent state for cell survival under glucose starvation is the final stage in the differentiation of hyphal cells and prerequisite for the production of derivatives of hyphal cells and for a control of their development."
5.	Infections 12/01/1996 - "antibacterial therapies, nutritional control, immunomodulation, removal of toxic substances, etc. Our attentions should be concentrated to prevent from septic MODF, especially for a patient primed by infection, because rapid response at the second at tack is important for care. "

Related Drugs and Biologics

1.	Anticoagulants
2.	Glucose (Dextrose)
3.	methyl 4,6- O- (1- carboxyethylidene)galactopyranoside

Related Therapies and Procedures

1.	Mechanical Ventilators (Ventilator)
2.	Immunomodulation
3.	Therapeutics
4.	Cardiopulmonary Bypass (Heart-Lung Bypass)