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isoapocodeine
RN given refers to (R)-isomer; structure given in first source
Networked:
2
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Alkaloids: 5398
Benzylisoquinolines: 151
Aporphines: 10
Apomorphine: 2080
isoapocodeine: 2
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Isoquinolines: 34
Benzylisoquinolines: 151
Aporphines: 10
Apomorphine: 2080
isoapocodeine: 2
4 or More Rings Heterocyclic Compounds
Aporphines: 10
Apomorphine: 2080
isoapocodeine: 2
Related Diseases
1.
Parkinson Disease (Parkinson's Disease)
05/01/1998 - "
The pharmacokinetics and metabolism of R-apomorphine were determined in 10 patients with idiopathic Parkinson's disease after intravenous infusion of 30 micrograms.kg-1 in 15 min. Specifically, emphasis was on enantiomeric interconversion into S-apomorphine and on the formation of apocodeine and isoapocodeine, since these metabolites may interfere with the pharmacodynamics of R-apomorphine.
"
05/01/1998 - "
The findings of this study show that on intravenous administration, S-apomorphine and the metabolites apocodeine and isoapocodeine are unlikely to interfere with the pharmacologic actions of R-apomorphine in patients with idiopathic Parkinson's disease.
"
11/21/1997 - "
Assay of R-apomorphine, S-apomorphine, apocodeine, isoapocodeine and their glucuronide and sulfate conjugates in plasma and urine of patients with Parkinson's disease.
"
Related Drugs and Biologics
1.
Apomorphine
2.
apocodeine
3.
Pharmacologic Actions
4.
Glucuronides
5.
Sulfates (Sulfates, Inorganic)
Related Therapies and Procedures
1.
Intravenous Administration
2.
Intravenous Infusions