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1-nitrosopyrene
structure given in first source
Networked:
4
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Pyrenes: 10
1-nitrosopyrene: 4
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Pyrenes: 10
1-nitrosopyrene: 4
Related Diseases
1.
Neoplasms (Cancer)
07/01/1988 - "
This study was carried out in order to evaluate possible mechanisms responsible for tumor induction by 1-nitropyrene and to provide insights on the higher tumorigenicity of 1-nitrosopyrene than 1-nitropyrene in newborn mouse liver.
"
08/01/1986 - "
The presumed proximate carcinogen, 1-nitrosopyrene, administered at 700 nmol per mouse, caused liver tumors in 45% of the males and in 9% of the females.
"
2.
Xeroderma Pigmentosum (Kaposi's Disease)
03/01/1988 - "
The cytotoxic effects of 1-nitropyrene and 1-nitrosopyrene were compared in fibroblasts from normal persons, from excision-repair-deficient xeroderma pigmentosum (XP) patients, and from a patient with an inherited predisposition to malignant melanoma of the skin (hereditary cutaneous malignant melanoma [HCMM]).
"
3.
Melanoma (Melanoma, Malignant)
03/01/1988 - "
The cytotoxic effects of 1-nitropyrene and 1-nitrosopyrene were compared in fibroblasts from normal persons, from excision-repair-deficient xeroderma pigmentosum (XP) patients, and from a patient with an inherited predisposition to malignant melanoma of the skin (hereditary cutaneous malignant melanoma [HCMM]).
"
4.
Adenocarcinoma
08/01/1988 - "
Percentages of incidences of mammary adenocarcinomas in female rats were as follows: 1-nitropyrene, high dose (63%); 1-nitropyrene, low dose (42%); 1-nitrosopyrene (19%); 1-aminopyrene (4%) trioctanoin (3%).
"
5.
Cutaneous Malignant Melanoma
03/01/1988 - "
The cytotoxic effects of 1-nitropyrene and 1-nitrosopyrene were compared in fibroblasts from normal persons, from excision-repair-deficient xeroderma pigmentosum (XP) patients, and from a patient with an inherited predisposition to malignant melanoma of the skin (hereditary cutaneous malignant melanoma [HCMM]).
"
Related Drugs and Biologics
1.
1-nitropyrene
2.
Carcinogens
3.
1-aminopyrene
4.
tricaprylin