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B 30-muramyl dipeptide

RN given refers to D-Gln-L-Ala isomer

Also Known As:

(B30)-MDP; 6-O-(2-tetradecyl-hexadecanoyl)-N-MDP; 6-O-(2-tetradecylhexadecanoyl)-N-acetylmuramyl-L-alanyl-D-isoglutamine; B30-MDP

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Amino Sugars: 110
  - Muramic Acids: 28
    - Acetylmuramyl-Alanyl-Isoglutamine: 467
      - B 30-muramyl dipeptide: 5
- Sugar Acids: 4
  - Muramic Acids: 28
    - Acetylmuramyl-Alanyl-Isoglutamine: 467
      - B 30-muramyl dipeptide: 5
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Glycopeptides: 1928
    - Acetylmuramyl-Alanyl-Isoglutamine: 467
      - B 30-muramyl dipeptide: 5

Related Diseases

1.	Hypersensitivity (Allergy) 01/01/1998 - "In addition, when mice were immunized once with B-1 vaccine admixed with or without B30-MDP and MDP-Lys(L18) and followed by intrafootpad (i.f.) injection of B-1 vaccine on day 7, mice immunized with B-1/B30-MDP and B-1/MDP-Lys(L18) induced a higher delayed-type hypersensitivity (DTH) reaction than mice immunized with B-1 vaccine alone. " 09/01/1986 - "B30-MDP was found to potently stimulate both humoral and cellular immune responses, the latter by induction of delayed-type hypersensitivity, irrespective of the administration vehicle examined (liposomes, a squalene in water emulsion, Intralipid, phosphate-buffered saline, and Nikkol HCO-60 glucose solution), although the minimum effective dose was dependent on the vehicle used. "
2.	Neoplasm Metastasis (Metastasis) 01/01/1992 - "Mice immunized with a mixture of X-irradiated tumour cells (10(3)) and B30-MDP (100 micrograms) on 7 days prior to challenge by viable tumour cells displayed a significant decrease in metastasis towards the target organs, liver and spleen, compared with that of untreated mice. "
3.	Lymphoma (Lymphomas) 01/01/1992 - "In contrast, cytotoxic activity of spleen cells against another target, L1210 lymphoma cells derived from BDF1 mice, was not observed by immunization with X-irradiated L5178Y-ML25 cells with or without B30-MDP. " 01/01/1992 - "Sensitization with X-irradiated tumour cells admixed with B30-MDP induced almost two times higher cytotoxicity of spleen cells against L5178Y-ML25 lymphoma cells than sensitization with X-irradiated tumour cells without B30-MDP. "
4.	Leukocytosis (Pleocytosis) 05/01/1991 - "Guinea-pigs which were injected repeatedly with a mixture of X-ray-treated leukaemic cells and B30-MDP dissolved in phosphate buffered saline resisted a challenge of leukaemia cells and showed no sign of leukocytosis. "
5.	Human Influenza (Influenza) 01/01/1997 - "Preparation of influenza virosome vaccine with muramyldipeptide derivative B30-MDP."

Related Drugs and Biologics

1.	Vaccines
2.	Phosphates (Orthophosphate)
3.	Virosomes
4.	Inactivated Vaccines
5.	Squalene
6.	Solutions
7.	Liposomes (Liposome)
8.	Glucose (Dextrose)
9.	Emulsions
10.	Acetylmuramyl-Alanyl-Isoglutamine