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N-chloroethylnitrosourea asparaginamide

structure given in first source; RN given refers to (S)-isomer

Also Known As:

AspCNU; N-chloroethylnitrosourea-L-asparaginamide

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Urea: 15015
    - Nitrosourea Compounds: 21
      - Carmustine: 2249
        N-chloroethylnitrosourea asparaginamide: 1
- Nitroso Compounds: 446
  - Nitrosourea Compounds: 21
    - Carmustine: 2249
      - N-chloroethylnitrosourea asparaginamide: 1

Related Diseases

1.	Meningioma (Meningiomas) 01/01/1985 - "In the one meningioma specimen, BCNU was significantly (P less than 0.05) more active than either AspCNU or SarCNU at all concentrations studied. "
2.	Glioma (Gliomas) 01/01/1985 - "These results suggest that AspCNU or SarCNU at doses that should produce less myelotoxicity than BCNU may be more active than BCNU against gliomas." 01/01/1985 - "AspCNU and SarCNU were significantly (P less than 0.05) more active than BCNU at 1-3 micrograms/ml concentrations in the HTSCA in all four malignant glioma specimens. "

Related Drugs and Biologics

1.	Carmustine (FIVB)
2.	2- ((((2- chloroethyl)nitrosoamino)carbonyl)amino)propanamide (SarCNU)