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hemoglobin Shelby

Glu replaced by Lys at position beta 131 (H9)

Also Known As:

Hb Deaconess; Hb Leslie; Hb Shelby; hemoglobin Deaconess; hemoglobin Leslie

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Hemoglobins: 37188
      - Abnormal Hemoglobins: 120
        hemoglobin Shelby: 3
  - Hemeproteins: 194
    - Globins: 2716
      - Hemoglobins: 37188
        Abnormal Hemoglobins: 120
        hemoglobin Shelby: 3

Related Diseases

1.	beta-Thalassemia (Cooley's Anemia) 01/01/1981 - "The subjects included normal adults (alpha alpha/alpha alpha) with or without a beta chain variant (Hb S, Hb Leslie) or an alpha chain variant (Hb G-Georgia); alpha-thalassemia-2 heterozygotes (alpha 0 alpha/alpha alpha) with an alpha chain variant (G-Georgia or G-Philadelphia); an alpha-thalassemia-1 heterozygote (alpha 0 alpha 0/alpha alpha); alpha-thalassemia-2 homozygotes (alpha 0 alpha 0/alpha 0 alpha) with a beta chain variant (Hb S), an alpha chain variant (G-Philadelphia), a Hb S homozygosity with Hb G-Philadelphia, or a Hb G-Philadelphia homozygosity; and three black beta +-thalassemia homozygotes. "
2.	Thalassemia 01/01/1992 - "Hb Shelby [alpha 2 beta 2(131)(H9)Gln----Lys]-beta zero-thalassemia [codon 15 (TGG----TGA)] identified by DNA sequencing."
3.	Anemia 01/01/1976 - "All persons with the various Hb Leslie combinations, including the propositus, have no clinical manifestations other than anemia. "

Related Drugs and Biologics

1.	DNA (Deoxyribonucleic Acid)
2.	Codon (Codons)
3.	hemoglobin G Georgia
4.	hemoglobin G Philadelphia