|1.||Kim, Youn-Chul: 2 articles (12/2011 - 10/2010)|
|2.||Kim, Eun-Cheol: 2 articles (12/2011 - 10/2010)|
|3.||Patnaik, Bharat Bhusan: 1 article (06/2015)|
|4.||Hur, Gang Min: 1 article (06/2015)|
|5.||Jung, Eui-Gil: 1 article (06/2015)|
|6.||Kwon, Hyun-Jung: 1 article (06/2015)|
|7.||Nam, Kung-Woo: 1 article (06/2015)|
|8.||Kim, Wan-Jong: 1 article (06/2015)|
|9.||Han, Man-Deuk: 1 article (06/2015)|
|10.||Han, Kook-Il: 1 article (06/2015)|
06/01/2015 - "Our results suggest that sappanchalcone could be used as an anti-inflammatory and bone-protective agent during the treatment of rheumatoid arthritis."
06/01/2015 - "We studied the efficacy of sappanchalcone in attenuating collagen-induced arthritis (CIA) in a mouse model of rheumatoid arthritis. "
|3.||Mouth Neoplasms (Oral Cancer)
12/01/2011 - "In this study, we examined whether sappanchalcone could inhibit the growth of human primary and metastatic oral cancer cells, and we analyzed the signaling pathway underlying the apoptotic effects of the compound in this process using 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyltetrazolium bromide (MTT) assays, fluorescence microscopy, flow cytometry, and Western blotting. "
12/01/2011 - "These results provide the first evidence that sappanchalcone suppresses oral cancer cell growth and induces apoptosis through the activation of p53-dependent mitochondrial, p38, ERK, JNK, and NF-κB signaling. "
12/01/2011 - "Mechanism of sappanchalcone-induced growth inhibition and apoptosis in human oral cancer cells."
12/01/2011 - "Sappanchalcone-treated oral cancer cells showed an increased cytosolic level of cytochrome c, downregulated Bcl-2 expression, upregulated Bax and p53 expression, caspase-3 and -9 activation, and poly (ADP-ribose) polymerase cleavage. "
10/10/2010 - "In this study, we examined the effects of sappanchalcone on hydrogen peroxide (H(2)O(2))-induced cytotoxicity using human dental pulp (HDP) cells, and lipopolysaccharide (LPS)-induced inflammation using human periodontal ligament (HPDL) cells. "
10/10/2010 - "Effects of sappanchalcone on the cytoprotection and anti-inflammation via heme oxygenase-1 in human pulp and periodontal ligament cells."
07/01/2009 - "Among the compounds tested, sappanchalcone (2) possessed the most potent effect against allergic reaction in RBL-2H3 cells with an inhibitory concentration (IC50) value of 7.6 microM, followed by 3-deoxysappanchalcone (1, IC50 = 15.3 microM), whereas other compounds showed moderate and mild effects. "
|1.||Hydrogen Peroxide (Hydroperoxide)
|2.||Caspase 3 (Caspase-3)
|4.||Cytochromes c (Cytochrome c)
|5.||Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)