|1.||Hong, Seung Hwan: 6 articles (08/2015 - 11/2004)|
|2.||Ahn, Young-Ho: 5 articles (08/2015 - 11/2004)|
|3.||Cho-Chung, Y S: 3 articles (07/2001 - 01/2000)|
|4.||Cho, Young Jun: 2 articles (08/2015 - 04/2013)|
|5.||Choi, Ki Young: 2 articles (08/2015 - 04/2013)|
|6.||Han, Jee Hae: 2 articles (01/2009 - 12/2006)|
|7.||Ruzdijić, Sabera: 2 articles (08/2008 - 01/2006)|
|8.||Nesterova, Maria: 2 articles (03/2008 - 06/2002)|
|9.||Kanazir, Selma: 2 articles (01/2006 - 01/2002)|
|10.||Jung, Joong Mok: 2 articles (06/2005 - 11/2004)|
11/01/2004 - "8-Chloro-cyclic AMP (8-Cl-cAMP) is known to be most effective in inducing growth inhibition and differentiation of a number of cancer cells. "
12/01/1996 - "In a recent phase I study conducted in cancer patients we have demonstrated that 8-Cl-cAMP, at doses devoid of toxicity, may achieve plasma concentrations in a range previously shown effective for cancer cell growth inhibition. "
11/15/1997 - "8-Chloro-cAMP (8-Cl-cAMP) is a novel agent that is able to inhibit the growth of a wide variety of cancer cell types in vitro and in vivo and, at doses devoid of toxicity, to achieve plasma concentrations in cancer patients in a range effective for cancer cell growth inhibition. "
08/07/2015 - "SHC1 sensitizes cancer cells to the 8-Cl-cAMP treatment."
04/01/2013 - "However, the exact mechanism of 8-Cl-cAMP functioning in cancer cells is not fully understood. "
07/31/2002 - "The present study was carried out to clarify overall cellular affects of 8-Cl-cAMP and 8-Cl-adenosine on SK-N-DZ human neuroblastoma cells by systematically characterizing gene expression using radioactive human cDNA microarray. "
01/01/2006 - "The combination of sulfinosine and 8-Cl-cAMP induces synergistic cell growth inhibition of the human neuroblastoma cell line in vitro."
01/01/2006 - "To identify purine analogs that could be effective in treating neuroblastomas, we tested the anticancer properties of sulfinosine, 8-Cl-cAMP and 8-Cl-adenosine in the SK-N-SH cell line. "
|3.||Prostatic Neoplasms (Prostate Cancer)
08/01/2008 - "The initial resistance to IR-induced apoptosis in these p53-deficient prostate cancer cell lines was overcome through an alternative proapoptotic pathway induced by 8-Cl-cAMP. "
08/01/2008 - "The antiproliferative and cytotoxic potential of the nucleotide analog 8-Cl-cAMP was tested in PC-3 and DU145 metastatic human prostate cancer cells. "
08/01/2008 - "The combination of gamma ionizing radiation and 8-Cl-cAMP induces synergistic cell growth inhibition and induction of apoptosis in human prostate cancer cells."
08/01/2008 - "Considering the low effective doses of treatments, improved tumor eradication rates and minimal undesirable side effects, the combination of IR and 8-Cl-cAMP could be the therapy of choice in treating prostate cancer."
|4.||Melanoma (Melanoma, Malignant)
12/01/2004 - "The aim of this work was the in vitro study of either 8-Cl-cAMP or TR effects on B16/F10 and B16/C3 mouse melanoma cell growth and cell death. "
11/15/1997 - "In this study, we have demonstrated that 8-Cl-cAMP, at a dose causing mild or no growth inhibition, synergistically increased the growth-inhibitory effect of paclitaxel or cisplatin in a wide series of cell lines including human breast, lung, ovary, colon, and head carcinomas and melanoma. "
|5.||Colonic Neoplasms (Colon Cancer)
12/01/1996 - "In the present study we have investigated the effect of 8-Cl-cAMP in association with cytotoxic drugs acting by different mechanisms of action on the growth of LS174T and GEO human colon cancer cells. "
12/01/1996 - "8-chloro-cAMP enhances the growth inhibitory effect of cytotoxic drugs in human colon cancer cells."
02/01/1995 - "A dose-dependent inhibition of monolayer cell growth was observed in two human colon cancer cell lines (GEO and CBS) and in a human breast cancer cell line (MDA-468) by treatment with either mAb 528 or 8-Cl-cAMP with 50% inhibitory concentration of 2-10 microgram/ml or 20-25 micrometer, respectively. "
09/01/1999 - "Synergistic growth inhibition and induction of apoptosis by a novel mixed backbone antisense oligonucleotide targeting CRIPTO in combination with C225 anti-EGFR monoclonal antibody and 8-Cl-cAMP in human GEO colon cancer cells."
11/15/1997 - "A cooperative antitumor effect was also observed in vivo, because treatment with paclitaxel followed by 8-Cl-cAMP markedly inhibited the growth of GEO human colon cancer xenografts as compared to paclitaxel alone without signs of toxicity. "
|3.||Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)
|4.||Cyclic AMP (AMP, Cyclic)
|5.||Transforming Growth Factor alpha (TGF-alpha)
|8.||Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
|9.||Tretinoin (Retinoic Acid)
|1.||Heterologous Transplantation (Xenotransplantation)
|2.||Drug Therapy (Chemotherapy)