HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
10-fluoro-7,12-dimethylbenz(a)anthracene
structure given in first source
Also Known As:
10-F-DMBA
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Benz(a)Anthracenes: 2
9,10-Dimethyl-1,2-benzanthracene: 979
10-fluoro-7,12-dimethylbenz(a)anthracene: 3
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Benz(a)Anthracenes: 2
9,10-Dimethyl-1,2-benzanthracene: 979
10-fluoro-7,12-dimethylbenz(a)anthracene: 3
Related Diseases
1.
Neoplasms (Cancer)
09/01/1986 - "
9-F-DMBA is equipotent, whereas 10-F-DMBA is more potent than DMBA for skin tumor initiation in this mouse stock.
"
08/01/1983 - "
We believe 10-F-DMBA to be the first example of a hydrocarbon with a fluoro substituent giving rise to increased tumor initiating activity.
"
02/01/1985 - "
The results suggest that the increased total binding and possibly the decreased proportion of syn-diol-epoxide:DNA adducts confer greater tumor-initiating potency on 10-F-DMBA.
"
02/01/1985 - "
Covalent binding of 7,12-dimethylbenz(a)anthracene and 10-fluoro-7,12-dimethylbenz(a)anthracene to mouse epidermal DNA and its relationship to tumor-initiating activity.
"
Related Drugs and Biologics
1.
DNA Adducts
2.
9,10-Dimethyl-1,2-benzanthracene
3.
Hydrocarbons
4.
Epoxy Compounds (Epoxides)
5.
DNA (Deoxyribonucleic Acid)